Nr 547 week 3 module info exam questions
& answers passed already graded a+
1. mesolimbic 7. nigrostriatal dopamine pathway: location
dopamine
pathway: 8. Nigrostriatal dopamine pathway: function
location
2. mesolimbic
dopamine
pathway:
function
3. mesolimb
ic
dopamin
e
pathway:
symptom
s
4. mesocortical
dopamine
pathway:
location
5. mesocortical
dopamine
pathway:
function
6. mesocortic
al
dopamine
pathway:
symptoms
1/
39
,Nr 547 week 3 module info exam questions
& answers passed already graded a+
ventral tegmental area (VTA) in
midbrain to the nucleus hypo activation may result in negative, cognitive and affective
accumbens (NAc) in the limbic symptoms
system
regulates emotional behaviors
and is also associated with projects from the substantia Niagara (in midbrain) to the basal ganglia
reward, motivation, pleasure
over activation leads to part of extrapyramidal nervous system which controls posture and
positive sx can be a voluntary motor movements.
downstream consequence of
prefrontal cortex (PFC)
dysfunction and glutamate
activity in the hypothalamus
VTA to PFC specifically affecting
the dorsolateral PFC and
ventromedial pre- frontal
cortex (VMPFC)
regulates cognition, executive
function, emotions and affect
-DLPFC cognitive/negative
symptoms
-VMPFC affect and negative
emotions
2/
39
,Nr 547 week 3 module info exam questions
& answers passed already graded a+
9. Nigrostriat imbalance here causes movement disorders ex. parkinsons disease
al and tremor low dopamine in basal ganglia cause akathisia and
dopamine dystonia
pathway:
hyper activation of this pathway results in tics, dyskinesias and
symptoms
chorea. chronic blockade leads to tardive dyskinesia
10. tuberoinfundib
projects from the hypothalamus to the anterior pituitary gland
u- lar
dopamine
pathway:
location
dopamine inhibits prolactin release from the pituitary
11. tuberoinfundib
u- lar
dopamine
disruption in this pathway leads to rising prolactin
pathway:
function levels=gynecomastia and galactorrhea in males and females, sexual
dysfunction and in females amenor- rhea
12. tuberoinfundibu
- lar dopamine
pathway:
symptoms
13. positive symptoms Delusions, hallucinations, excitability, thought disorders, hostility
of schizophrenia
14. negative 15. motor symptoms of schizophrenia
symt- poms
of Schizo- 16. Affective symp- toms of schizo- phrenia
phrenia
3/
39
, Nr 547 week 3 module info exam questions
& answers passed already graded a+
a logia
t asociality
t amotivation
e
c motor delay, dyscoordination, extrapyramidal symptoms ex. parkinsons,
t dyski- nesia
i
Depression
v
Anxiety
e
Suicidality
f
l
a
t
t
e
n
i
n
g
a
n
h
e
d
o
n
i
a
a
4/
39
& answers passed already graded a+
1. mesolimbic 7. nigrostriatal dopamine pathway: location
dopamine
pathway: 8. Nigrostriatal dopamine pathway: function
location
2. mesolimbic
dopamine
pathway:
function
3. mesolimb
ic
dopamin
e
pathway:
symptom
s
4. mesocortical
dopamine
pathway:
location
5. mesocortical
dopamine
pathway:
function
6. mesocortic
al
dopamine
pathway:
symptoms
1/
39
,Nr 547 week 3 module info exam questions
& answers passed already graded a+
ventral tegmental area (VTA) in
midbrain to the nucleus hypo activation may result in negative, cognitive and affective
accumbens (NAc) in the limbic symptoms
system
regulates emotional behaviors
and is also associated with projects from the substantia Niagara (in midbrain) to the basal ganglia
reward, motivation, pleasure
over activation leads to part of extrapyramidal nervous system which controls posture and
positive sx can be a voluntary motor movements.
downstream consequence of
prefrontal cortex (PFC)
dysfunction and glutamate
activity in the hypothalamus
VTA to PFC specifically affecting
the dorsolateral PFC and
ventromedial pre- frontal
cortex (VMPFC)
regulates cognition, executive
function, emotions and affect
-DLPFC cognitive/negative
symptoms
-VMPFC affect and negative
emotions
2/
39
,Nr 547 week 3 module info exam questions
& answers passed already graded a+
9. Nigrostriat imbalance here causes movement disorders ex. parkinsons disease
al and tremor low dopamine in basal ganglia cause akathisia and
dopamine dystonia
pathway:
hyper activation of this pathway results in tics, dyskinesias and
symptoms
chorea. chronic blockade leads to tardive dyskinesia
10. tuberoinfundib
projects from the hypothalamus to the anterior pituitary gland
u- lar
dopamine
pathway:
location
dopamine inhibits prolactin release from the pituitary
11. tuberoinfundib
u- lar
dopamine
disruption in this pathway leads to rising prolactin
pathway:
function levels=gynecomastia and galactorrhea in males and females, sexual
dysfunction and in females amenor- rhea
12. tuberoinfundibu
- lar dopamine
pathway:
symptoms
13. positive symptoms Delusions, hallucinations, excitability, thought disorders, hostility
of schizophrenia
14. negative 15. motor symptoms of schizophrenia
symt- poms
of Schizo- 16. Affective symp- toms of schizo- phrenia
phrenia
3/
39
, Nr 547 week 3 module info exam questions
& answers passed already graded a+
a logia
t asociality
t amotivation
e
c motor delay, dyscoordination, extrapyramidal symptoms ex. parkinsons,
t dyski- nesia
i
Depression
v
Anxiety
e
Suicidality
f
l
a
t
t
e
n
i
n
g
a
n
h
e
d
o
n
i
a
a
4/
39
