CURRENT MEDICAL DIAGNOSIS AND
TREATMENT 2026
65TH EDITION
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
1)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Colorectal
Cancer Screening
Stem
A 48-year-old asymptomatic man with no family history of
colorectal cancer presents for a routine health visit and asks
when to begin colorectal screening. His last outpatient labs
,were normal, and he has no red-flag symptoms. What is the
most appropriate next step?
Options
A. Defer screening until age 50 because he is low risk.
B. Begin screening now — offer colonoscopy every 10 years or
stool-based testing per shared decision-making.
C. Order a one-time CT colonography only.
D. Perform fecal occult blood testing only every 5 years.
Correct answer
B
Rationale — Correct (B)
CMDT endorses initiating average-risk colorectal cancer
screening beginning at age 45; at age 48 the patient should be
offered screening now with either colonoscopy (every 10 years
if normal) or stool-based testing (eg, annual FIT) based on
shared decision-making. This choice balances test sensitivity,
prevention (polypectomy), and patient preferences. (CMDT Ch.
1 recommendations.) USPSTF
Rationale — Incorrect
A. Deferring to 50 is outdated; guidance supports starting at 45.
C. CT colonography is an acceptable modality in some settings
but is not the sole recommended test; colonoscopy or stool
testing are standard first-line options.
D. FOBT every 5 years is not guideline-concordant; modern
stool testing intervals differ (eg, annual FIT).
,Teaching point (≤20 words)
Average-risk colorectal screening should begin at age 45—
choose colonoscopy or stool testing via shared decision-making.
Citation (APA)
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Lung Cancer
Screening
Stem
A 62-year-old man with a 40 pack-year smoking history who
quit 8 years ago asks about lung cancer screening. He is
otherwise functionally independent and wants your
recommendation.
Options
A. No screening indicated because he quit >5 years ago.
B. Annual low-dose CT (LDCT) screening is recommended given
his smoking history and age.
C. Obtain a chest radiograph annually.
D. Only screen if he develops respiratory symptoms.
Correct answer
B
, Rationale — Correct (B)
CMDT endorses annual low-dose CT for high-risk individuals
(age and cumulative smoking exposure) who are current
smokers or quit within the defined timeframe used by major
guidelines; LDCT reduces lung-cancer mortality compared with
chest radiography and is the recommended screening modality
for appropriately selected high-risk patients. The patient’s age
and 40 pack-year history make him eligible.
accessmedicine.mhmedical.com+1
Rationale — Incorrect
A. Quit >5 years does not automatically exclude eligibility —
selection depends on age and pack-year history per guideline
thresholds.
C. Chest radiograph is not recommended for screening; it does
not reduce mortality.
D. Waiting for symptoms misses the benefit of early detection
and is not guideline-based.
Teaching point
Annual LDCT for lung cancer is indicated in appropriately
selected high-risk adults.
Citation (APA)
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
3)
TREATMENT 2026
65TH EDITION
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
1)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Colorectal
Cancer Screening
Stem
A 48-year-old asymptomatic man with no family history of
colorectal cancer presents for a routine health visit and asks
when to begin colorectal screening. His last outpatient labs
,were normal, and he has no red-flag symptoms. What is the
most appropriate next step?
Options
A. Defer screening until age 50 because he is low risk.
B. Begin screening now — offer colonoscopy every 10 years or
stool-based testing per shared decision-making.
C. Order a one-time CT colonography only.
D. Perform fecal occult blood testing only every 5 years.
Correct answer
B
Rationale — Correct (B)
CMDT endorses initiating average-risk colorectal cancer
screening beginning at age 45; at age 48 the patient should be
offered screening now with either colonoscopy (every 10 years
if normal) or stool-based testing (eg, annual FIT) based on
shared decision-making. This choice balances test sensitivity,
prevention (polypectomy), and patient preferences. (CMDT Ch.
1 recommendations.) USPSTF
Rationale — Incorrect
A. Deferring to 50 is outdated; guidance supports starting at 45.
C. CT colonography is an acceptable modality in some settings
but is not the sole recommended test; colonoscopy or stool
testing are standard first-line options.
D. FOBT every 5 years is not guideline-concordant; modern
stool testing intervals differ (eg, annual FIT).
,Teaching point (≤20 words)
Average-risk colorectal screening should begin at age 45—
choose colonoscopy or stool testing via shared decision-making.
Citation (APA)
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Lung Cancer
Screening
Stem
A 62-year-old man with a 40 pack-year smoking history who
quit 8 years ago asks about lung cancer screening. He is
otherwise functionally independent and wants your
recommendation.
Options
A. No screening indicated because he quit >5 years ago.
B. Annual low-dose CT (LDCT) screening is recommended given
his smoking history and age.
C. Obtain a chest radiograph annually.
D. Only screen if he develops respiratory symptoms.
Correct answer
B
, Rationale — Correct (B)
CMDT endorses annual low-dose CT for high-risk individuals
(age and cumulative smoking exposure) who are current
smokers or quit within the defined timeframe used by major
guidelines; LDCT reduces lung-cancer mortality compared with
chest radiography and is the recommended screening modality
for appropriately selected high-risk patients. The patient’s age
and 40 pack-year history make him eligible.
accessmedicine.mhmedical.com+1
Rationale — Incorrect
A. Quit >5 years does not automatically exclude eligibility —
selection depends on age and pack-year history per guideline
thresholds.
C. Chest radiograph is not recommended for screening; it does
not reduce mortality.
D. Waiting for symptoms misses the benefit of early detection
and is not guideline-based.
Teaching point
Annual LDCT for lung cancer is indicated in appropriately
selected high-risk adults.
Citation (APA)
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
3)
