CURRENT MEDICAL DIAGNOSIS AND
TREATMENT 2026
65TH EDITION
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
1)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Adult
Immunizations (influenza)
Stem
A 72-year-old man with well-controlled type 2 diabetes and
chronic obstructive pulmonary disease presents for annual
preventive care in October. He received an inactivated influenza
,vaccine last year but cannot recall the formulation. Which
action is most appropriate now?
A. Offer standard-dose quadrivalent inactivated influenza
vaccine.
B. Offer high-dose or adjuvanted influenza vaccine appropriate
for older adults.
C. Defer vaccination until local influenza activity peaks.
D. Offer live attenuated intranasal influenza vaccine.
Correct answer: B
Rationale — Correct (B)
CMDT emphasizes that adults ≥65 years should receive an
influenza vaccine formulation optimized for older adults (high-
dose or adjuvanted) to improve immune response and reduce
severe outcomes. For a 72-year-old with comorbidity, the high-
dose/adjuvanted option is preferred. (CMDT 2026 prevention
chapter).
Rationales — Incorrect
A. Standard-dose vaccines are acceptable if optimized
formulations unavailable, but less preferred in ≥65-year-olds.
C. Deferring vaccination risks missing protection — vaccinate
before influenza season begins.
D. Live intranasal vaccine is contraindicated or not
recommended for older adults and those with chronic
cardiopulmonary disease.
,Teaching point
Use age-optimized (high-dose/adjuvanted) influenza vaccine for
people ≥65 years.
Citation
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion — HPV
Vaccination
Stem
A 36-year-old woman requests HPV vaccination. She has had
prior sexual partners but is currently in a monogamous
relationship and has no history of cervical dysplasia. What is the
best counseling and management approach?
A. HPV vaccination is not effective after age 30; decline
vaccination.
B. Recommend routine vaccination — give full 3-dose series
immediately.
C. Discuss shared clinical decision-making; vaccination may offer
benefit and can be given.
D. Only vaccinate if the patient reports new sexual partners in
the past year.
Correct answer: C
, Rationale — Correct (C)
CMDT aligns with guidance that for adults 27–45, HPV
vaccination is considered based on shared clinical decision-
making because benefit is smaller than in younger persons but
may help those with new exposure risk. Offer informed
discussion and vaccinate if patient chooses.
Rationales — Incorrect
A. Vaccine is not categorically ineffective after 30; many
guidelines allow shared decision-making through age 45.
B. Routine universal vaccination is for younger cohorts
(adolescents and up to mid-20s); 3-dose schedule depends on
age and prior dosing.
D. Vaccination decisions should be individualized, not limited
strictly to recent new partners.
Teaching point
Offer HPV vaccination by shared decision-making for adults 27–
45.
Citation
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
3)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Cervical
Cancer Screening
TREATMENT 2026
65TH EDITION
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
1)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Adult
Immunizations (influenza)
Stem
A 72-year-old man with well-controlled type 2 diabetes and
chronic obstructive pulmonary disease presents for annual
preventive care in October. He received an inactivated influenza
,vaccine last year but cannot recall the formulation. Which
action is most appropriate now?
A. Offer standard-dose quadrivalent inactivated influenza
vaccine.
B. Offer high-dose or adjuvanted influenza vaccine appropriate
for older adults.
C. Defer vaccination until local influenza activity peaks.
D. Offer live attenuated intranasal influenza vaccine.
Correct answer: B
Rationale — Correct (B)
CMDT emphasizes that adults ≥65 years should receive an
influenza vaccine formulation optimized for older adults (high-
dose or adjuvanted) to improve immune response and reduce
severe outcomes. For a 72-year-old with comorbidity, the high-
dose/adjuvanted option is preferred. (CMDT 2026 prevention
chapter).
Rationales — Incorrect
A. Standard-dose vaccines are acceptable if optimized
formulations unavailable, but less preferred in ≥65-year-olds.
C. Deferring vaccination risks missing protection — vaccinate
before influenza season begins.
D. Live intranasal vaccine is contraindicated or not
recommended for older adults and those with chronic
cardiopulmonary disease.
,Teaching point
Use age-optimized (high-dose/adjuvanted) influenza vaccine for
people ≥65 years.
Citation
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
2)
Reference
Ch. 1 — Disease Prevention & Health Promotion — HPV
Vaccination
Stem
A 36-year-old woman requests HPV vaccination. She has had
prior sexual partners but is currently in a monogamous
relationship and has no history of cervical dysplasia. What is the
best counseling and management approach?
A. HPV vaccination is not effective after age 30; decline
vaccination.
B. Recommend routine vaccination — give full 3-dose series
immediately.
C. Discuss shared clinical decision-making; vaccination may offer
benefit and can be given.
D. Only vaccinate if the patient reports new sexual partners in
the past year.
Correct answer: C
, Rationale — Correct (C)
CMDT aligns with guidance that for adults 27–45, HPV
vaccination is considered based on shared clinical decision-
making because benefit is smaller than in younger persons but
may help those with new exposure risk. Offer informed
discussion and vaccinate if patient chooses.
Rationales — Incorrect
A. Vaccine is not categorically ineffective after 30; many
guidelines allow shared decision-making through age 45.
B. Routine universal vaccination is for younger cohorts
(adolescents and up to mid-20s); 3-dose schedule depends on
age and prior dosing.
D. Vaccination decisions should be individualized, not limited
strictly to recent new partners.
Teaching point
Offer HPV vaccination by shared decision-making for adults 27–
45.
Citation
Papadakis, M. A., McPhee, S. J., & Rabow, M. W. (2026). Current
Medical Diagnosis & Treatment (65th ed.). Ch. 1.
3)
Reference
Ch. 1 — Disease Prevention & Health Promotion — Cervical
Cancer Screening
