TABLE OF CONTENT
x@ x@
Chapterx @ 1:x @ Pharmacokinetics
Chapterx@2:x@Drug–
Receptorx@Interactionsx@andx@Pharmacodynamicsx @ Chapterx@3:x @
Thex @ Autonomicx@Nervousx@System
Chapterx@4:x@Cholinergicx@Agonistsx
@Chapterx@5:x@Cholinergicx@Antagon
istsx@Chapterx@6:x@Adrenergicx@Agon
istsx@Chapterx@7:x@Adrenergicx@Anta
gonists
Chapterx@8:x@Drugsx@forx@Neurodegenerativex@Diseases
x@Chapterx@9: x@Anxiolytic x@andx@Hypnoticx@Drugs
Chapterx@10:x@Antidepressantsx@Cha
pterx@11:x@Antipsychoticx@Drugsx@C
hapterx@12:x@Drugsx@forx@Epilepsyx@
Chapterx@13:x@Anesthetics
Chapterx @ 14:x @ Opioids
Chapterx@15:x@Drugsx@ofx@Abusex@C
hapterx@16:x@CNSx@Stimulantsx@Cha
pterx@17:x@Antihypertensivesx@Chapt
erx@18:x@Diuretics
Chapterx @ 19:x @ Heartx @ Failure
Chapterx@20:x@Antiarrhythmicsx@Cha
pterx@21:x@Antianginalx@Drugs
Chapterx@22:x@Anticoagulantsx@andx@Antiplateletx@Age
ntsx @ Chapterx@23:x@Drugsx@forx@Hyperlipidemia
Chapterx@24:x@Pituitaryx@andx@Thyroi
dx@Chapterx@25:x@Drugsx@forx@Diabet
es
Chapterx@26:x@Estrogensx@andx@Androgensx@C
hapterx@27:x@Adrenalx@Hormones
Chapterx @ 28:x @ Drugsx @ forx @ Obesity
Chapterx@29:x@Drugsx@forx@Disordersx@ofx@thex@Respiratoryx@System
x @ Chapterx@30:x@Antihistamines
Chapterx@31:x@Gastrointestinalx@andx@Antiemeticx@Drug
sx@Chapterx@32:x@Drugsx@forx@Urologicx @ Disorders
Chapterx @ 33:x @ Drugsx @ forx @ Anemia
Chapterx@34:x@Drugsx@forx@Dermatologicx@Disordersx@C
hapterx@35:x@Drugsx@forx@Bonex@Disorders
Chapterx@36:x@Anti-
inflammatory,x@Antipyretic,x@andx @ Analgesicx@Agentsx @ Chapterx@37:x @ Pri
nciplesx@ofx @ Antimicrobialx @ Therapy
Chapterx @ 38:x @ Cellx@ Wallx @ Inhibitors
Chapterx @ 39:x @ Proteinx @ Synthesisx @ Inhibitors
Chapterx@40:x@Quinolones,x@Folicx@Acidx @ Antagonists,x @ andx @ Urinaryx @ Tractx@Antisept
icsx@Chapterx@41:x@Antimycobacterialx@Drugs
Chapterx@42:x@Antifungalx@Drugsx@C
hapterx@43:x@Antiprotozoalx@Drugsx@
Chapterx@44:x@Anthelminticx@Drugsx
@Chapterx@45:x@Antiviral x@Drugs
Chapterx @ 46:x @ Anticancerx @ Drugs
Chapter 47: Immunosuppressants
,
,
, 3. The nurse is teaching a patient who will be discharged home with a prescription for an
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
enteric-
x@ coated tablet. Which statement by the patient indicates understanding of the teaching?
x@ x@ x@ x@ x@ x@ x @ x@ x@ x@ x@
a. I may crush the tablet and put it in applesauce to improve absorption.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
b. I should consume acidic foods to enhance absorption of this medication.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
c. I should expect a delay in onset of the drugs effects after taking the tablet.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
d. I should take this medication with high-
x@ x@ x@ x@ x@ x@
fat foods to improve its action. ANS: C
x@ x@ x@ x@ x@ x@ x@
Enteric-
coated tablets resist disintegration in the acidic environment of the stomach and disintegr
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ate when they reach the small intestine. There is usually some delay in onset of actions a
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
fter taking these medications. Enteric-
x@ x@ x@ x@
coated tablets should not be crushed or chewed, which would alter the time and location
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
of absorption. Acidic foods will not enhance the absorption of the medication. The patient
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
should not to eat high-fat food before ingesting an enteric-coated tablet, because high-
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
fat foods decrease the absorption rate.
x@ x@ x@ x@ x@
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
x@ x@ x@ x@ x@ x@ x@
TOP: NURSING PROCESS: Nursing Intervention
x@ x@ x@ x@ x@
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
x@ x@ x@ x@ x@ x@ x@
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin mu
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
st be given by subcutaneous injection instead of by mouth. The nurse will explain that th
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
is is because
x@ x@
a. absorption is diminished by the first-pass effects in the liver.
x@ x@ x@ x@ x@ x@ x@ x@ x@
b. absorption is faster when insulin is given subcutaneously.
x@ x@ x@ x@ x@ x@ x@
c. digestive enzymes in the gastrointestinal tract prevent absorption.
x@ x@ x@ x@ x@ x@ x@
d. the oral form is less predictable with more adverse eff
x@ x@ x@ x@ x@ x@ x@ x@ x@
ects. ANS: C x@ x@
Insulin, growth hormones, and other protein-
x@ x@ x@ x@ x@
based drugs are destroyed in the small intestine by digestive enzymes and must be given
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
parenterally. Because insulin is destroyed by digestive enzymes, it would not make it to t
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
he liver for metabolism with a first-
x@ x@ x@ x@ x@ x@
pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in such
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
Pagex @ 2x @ ofx @ 507
x@ x@
Chapterx @ 1:x @ Pharmacokinetics
Chapterx@2:x@Drug–
Receptorx@Interactionsx@andx@Pharmacodynamicsx @ Chapterx@3:x @
Thex @ Autonomicx@Nervousx@System
Chapterx@4:x@Cholinergicx@Agonistsx
@Chapterx@5:x@Cholinergicx@Antagon
istsx@Chapterx@6:x@Adrenergicx@Agon
istsx@Chapterx@7:x@Adrenergicx@Anta
gonists
Chapterx@8:x@Drugsx@forx@Neurodegenerativex@Diseases
x@Chapterx@9: x@Anxiolytic x@andx@Hypnoticx@Drugs
Chapterx@10:x@Antidepressantsx@Cha
pterx@11:x@Antipsychoticx@Drugsx@C
hapterx@12:x@Drugsx@forx@Epilepsyx@
Chapterx@13:x@Anesthetics
Chapterx @ 14:x @ Opioids
Chapterx@15:x@Drugsx@ofx@Abusex@C
hapterx@16:x@CNSx@Stimulantsx@Cha
pterx@17:x@Antihypertensivesx@Chapt
erx@18:x@Diuretics
Chapterx @ 19:x @ Heartx @ Failure
Chapterx@20:x@Antiarrhythmicsx@Cha
pterx@21:x@Antianginalx@Drugs
Chapterx@22:x@Anticoagulantsx@andx@Antiplateletx@Age
ntsx @ Chapterx@23:x@Drugsx@forx@Hyperlipidemia
Chapterx@24:x@Pituitaryx@andx@Thyroi
dx@Chapterx@25:x@Drugsx@forx@Diabet
es
Chapterx@26:x@Estrogensx@andx@Androgensx@C
hapterx@27:x@Adrenalx@Hormones
Chapterx @ 28:x @ Drugsx @ forx @ Obesity
Chapterx@29:x@Drugsx@forx@Disordersx@ofx@thex@Respiratoryx@System
x @ Chapterx@30:x@Antihistamines
Chapterx@31:x@Gastrointestinalx@andx@Antiemeticx@Drug
sx@Chapterx@32:x@Drugsx@forx@Urologicx @ Disorders
Chapterx @ 33:x @ Drugsx @ forx @ Anemia
Chapterx@34:x@Drugsx@forx@Dermatologicx@Disordersx@C
hapterx@35:x@Drugsx@forx@Bonex@Disorders
Chapterx@36:x@Anti-
inflammatory,x@Antipyretic,x@andx @ Analgesicx@Agentsx @ Chapterx@37:x @ Pri
nciplesx@ofx @ Antimicrobialx @ Therapy
Chapterx @ 38:x @ Cellx@ Wallx @ Inhibitors
Chapterx @ 39:x @ Proteinx @ Synthesisx @ Inhibitors
Chapterx@40:x@Quinolones,x@Folicx@Acidx @ Antagonists,x @ andx @ Urinaryx @ Tractx@Antisept
icsx@Chapterx@41:x@Antimycobacterialx@Drugs
Chapterx@42:x@Antifungalx@Drugsx@C
hapterx@43:x@Antiprotozoalx@Drugsx@
Chapterx@44:x@Anthelminticx@Drugsx
@Chapterx@45:x@Antiviral x@Drugs
Chapterx @ 46:x @ Anticancerx @ Drugs
Chapter 47: Immunosuppressants
,
,
, 3. The nurse is teaching a patient who will be discharged home with a prescription for an
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
enteric-
x@ coated tablet. Which statement by the patient indicates understanding of the teaching?
x@ x@ x@ x@ x@ x@ x @ x@ x@ x@ x@
a. I may crush the tablet and put it in applesauce to improve absorption.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
b. I should consume acidic foods to enhance absorption of this medication.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
c. I should expect a delay in onset of the drugs effects after taking the tablet.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
d. I should take this medication with high-
x@ x@ x@ x@ x@ x@
fat foods to improve its action. ANS: C
x@ x@ x@ x@ x@ x@ x@
Enteric-
coated tablets resist disintegration in the acidic environment of the stomach and disintegr
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
ate when they reach the small intestine. There is usually some delay in onset of actions a
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
fter taking these medications. Enteric-
x@ x@ x@ x@
coated tablets should not be crushed or chewed, which would alter the time and location
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
of absorption. Acidic foods will not enhance the absorption of the medication. The patient
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
should not to eat high-fat food before ingesting an enteric-coated tablet, because high-
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
fat foods decrease the absorption rate.
x@ x@ x@ x@ x@
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
x@ x@ x@ x@ x@ x@ x@
TOP: NURSING PROCESS: Nursing Intervention
x@ x@ x@ x@ x@
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
x@ x@ x@ x@ x@ x@ x@
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin mu
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
st be given by subcutaneous injection instead of by mouth. The nurse will explain that th
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
is is because
x@ x@
a. absorption is diminished by the first-pass effects in the liver.
x@ x@ x@ x@ x@ x@ x@ x@ x@
b. absorption is faster when insulin is given subcutaneously.
x@ x@ x@ x@ x@ x@ x@
c. digestive enzymes in the gastrointestinal tract prevent absorption.
x@ x@ x@ x@ x@ x@ x@
d. the oral form is less predictable with more adverse eff
x@ x@ x@ x@ x@ x@ x@ x@ x@
ects. ANS: C x@ x@
Insulin, growth hormones, and other protein-
x@ x@ x@ x@ x@
based drugs are destroyed in the small intestine by digestive enzymes and must be given
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
parenterally. Because insulin is destroyed by digestive enzymes, it would not make it to t
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
he liver for metabolism with a first-
x@ x@ x@ x@ x@ x@
pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in such
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@ x@
Pagex @ 2x @ ofx @ 507