Lucyjonnes

-Block the bone marrow, bowel and bladder -Sometimes the ovaries and testis Typical Tx Dose: - Answers-Tx Dose: -Non-bulky, Stage 1 and 2: 20-30 Gy -All Stages: Bulky disease (>10 cm in diameter): 30-36 Gy Hodgkin Lymphoma: Abdominal (Periaortic) Portion of the Inverted Y Field: - Answers-Tx Borders: -Superior: approximately mid T-10, with an appropriate gap from the mantle field -Inferior: L4-L5 -Lateral: usually 9-10 cm wide, may encompass the spleen or splenic pedicle) ...

How is non-Hodgkin's Lymphoma classified? - Answers-According to different cellular characteristics and lymph node characteristics. Why is non-Hodgkin's Lymphoma "worse" than Hodgkin's Lymphoma? - Answers-Widely disseminated disease is usually present at time of diagnosis. Non-Hodgkin's Lymphoma can be classified as either aggressive (fast-growing) or__________________? - Answers-Indolent (slow-growing). What is the most commonly occurring hematologic cancer? Why has it increased?...

Rationale: Up to 90% of clients respond well to standard treatment with chemotherapy and radiation therapy, and those who relapse usually respond to a change of chemotherapy medications. Survival depends on the individual client and the stage of disease at diagnosis. Why it's not the rest: Investigational therapy regimens would not be recommended for clients initially diagnosed with Hodgkin's disease because of the expected prognosis with standard therapy. Clients usually achieve a signific...

In what kind of non-Hodgkin's lymphoma is there increased LDH in? - Answers-In rapidly proliferating and extensive disease, serum uric acid may also be increased List the favourable prognostic factors for high grade non-Hodgkin's lymphoma - Answers-Age under 60 years, stage I or II, normal serum LDH, 0 or 1 extranodal sites, a performance status of 0 or 1 List the unfavourable prognostic factors for high grade non-Hodgkin's lymphoma - Answers-Age over 60 years, stage III or IV, increase...

What is the most common form of NHL and how does it present? - Answers-Follicular lymphoma (indolent) - asymptomatic, painless, diffuse, long-standing peripheral lymphadenopathy in middle-aged individual or elderly - Bone marrow involvement and disseminated disease is present in majority When should follicular lymphoma be treated? - Answers-only if symptomatic (or high-grade presentation) - alkylating agent - rituximab - steroids What type of lymphoma is small lymphocytic lymphoma? - ...

**What is the bone disease due to in Multiple Myeloma/MGUS? - Answers-Stimulation of osteoclasts and inhibition of osteoblasts What are Plasmacytomas in Multiple Myeloma/MGUS? - Answers-Isolated tumor composed of clonal plasma cells, often occurring on the ribs or other flat bones What kind of lesion should I expect to see in Multiple Myeloma? - Answers-Lytic (NOT blastic) lesions Why are bone scans very low yield in Multiple Myeloma? - Answers-It detects only blastic lesions What is...

Chest x-ray: large mediastinal mass - Answers-Suspect a diagnosis of lymphoma, refer to a surgeon for excisional biopsy of cervical lymph node (FNAB sufficient). Pathology shows Classical Hodgkin lymphoma, nodular sclerosing subtype. What should you look for in the history (if lymphoma is suspected? - Answers-HISTORY — History of the lymph node — when it first appeared, rapidity of growth, any pain — B-symptoms (weight loss, fever, night sweats) — Pruritus, lymph node pain wi...

Chronic Lymphocytic Leukemia (CLL) - Answers-1) 2/3 patients greater than 60 years old more in males 2) Rare under 50 years old 3) Most common leukemia in US adults 4) Survival 2-14 years 5) Cells fully mature and abnormal; cells don't die so accumulate in the blood Chronic Lymphocytic Leukemia - General Pathophysiology - Answers-1) Derived from B-lymphs 2) Cells fully mature 3) Escape apoptosis (cell death)- increased cells in marrow and circulation Chronic Lymphocytic Leukemia - E...

Stage IIIA is treated with: - Answers-radiation therapy and chemotherapy These stages can be cured with high-dose chemotherapy and bone marrow or peripheral stem cell transplant - Answers-some stage IIIB and IV therapy must be _______. - Answers-aggressive This does not contribute to increased survival once a complete remission has been achieved - Answers-maintenance chemotherapy % of risk for secondary cancer at 15 years after tx - Answers-18% Most common types of secondary cance...

1. Follicular lymphoma is the most common form of NHL. - Anwers-ANS: F NHLs can be histopathologically classified as follicular (or nodular) and diffuse, with 40% appearing as follicular and 60% as diffuse. 2. HD can be treated with mantle, para-aortic, and inverted-Y fields. - Anwers-ANS: T HD can be treated with mantle, para-aortic, and inverted-Y fields (sometimes the para-aortic field is included as part of the overall term "inverted-Y"). REF: Chapter 29, Lymphoreticular System Tumor...