Exam 5 Study Guide

Musculoskeletal

Define differences between bone cells



•	Osteogenic cell: stem cell

•	Osteoblasts: bone forming cells, “bone-builders”

o	Derived from mesenchymal cells

o	Produce osteocalcin when stimulated by vitamin D

o	Form new bone – synthesize osteoid – brings on the formation of new bone – nonmineralized bone matrix

o	Follow Wolfe’s law: bone is shaped according to its function

o	Become osteocytes that are imbedded in bone

•	Osteoclasts: bone ...