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MGY 250 Final Exam Study Guide Questions with Correct Answers Latest Update 2025/2026
MGY 250 Final Exam Study Guide Questions with Correct Answers Latest Update 2025/2026 
Hierarchical shotgun sequencing - Answers Break up DNA, sequence and find overlapping pieces, then assemble 
Purpose of hierarchical shotgun sequencing - Answers Could be a way to reconstitute an accurate assembly 
DNA cloning - Answers Assemble recombinant DNA and direct their replication within model organisms 
Purpose of DNA cloning - Answers Produce a large quantity of a single gene 
Sanger sequencing - An...
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- • 27 pages •
MGY 250 Final Exam Study Guide Questions with Correct Answers Latest Update 2025/2026 
Hierarchical shotgun sequencing - Answers Break up DNA, sequence and find overlapping pieces, then assemble 
Purpose of hierarchical shotgun sequencing - Answers Could be a way to reconstitute an accurate assembly 
DNA cloning - Answers Assemble recombinant DNA and direct their replication within model organisms 
Purpose of DNA cloning - Answers Produce a large quantity of a single gene 
Sanger sequencing - An...
MGY 250 Unit 7 Quiz Questions with Verified Solutions Latest Update 2025/2026
MGY 250 Unit 7 Quiz Questions with Verified Solutions Latest Update 2025/2026 
Which of the following are ways that tumours can be generated in mice (select all that apply): 
 
Inoculating an immunocompetent mouse with human tumour cells 
Genetically engineer a mouse with specific mutations to generate tumours 
Treat a mouse with carcinogens to generate tumours 
Inoculating an immunosuppressed mouse with human tumour cells - Answers Genetically engineer a mouse with specific mutations to generat...
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- • 7 pages •
MGY 250 Unit 7 Quiz Questions with Verified Solutions Latest Update 2025/2026 
Which of the following are ways that tumours can be generated in mice (select all that apply): 
 
Inoculating an immunocompetent mouse with human tumour cells 
Genetically engineer a mouse with specific mutations to generate tumours 
Treat a mouse with carcinogens to generate tumours 
Inoculating an immunosuppressed mouse with human tumour cells - Answers Genetically engineer a mouse with specific mutations to generat...
MGY 250 Unit 9 Quiz Questions with Correct Answers Latest Update 2025/2026
MGY 250 Unit 9 Quiz Questions with Correct Answers Latest Update 2025/2026 
Microsatellite instability analysis involves: 
 
Examining tumour tissue microsatellite stability, which would suggest a mutation in APC 
Examining tumour tissue microsatellite stability, which would suggest an error in mismatch repair 
The comparison of normal and tumour tissue to determine if tumour tissue has relatively high levels of microsatellite instability, which would suggest an error in mismatch repair 
The com...
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MGY 250 Unit 9 Quiz Questions with Correct Answers Latest Update 2025/2026 
Microsatellite instability analysis involves: 
 
Examining tumour tissue microsatellite stability, which would suggest a mutation in APC 
Examining tumour tissue microsatellite stability, which would suggest an error in mismatch repair 
The comparison of normal and tumour tissue to determine if tumour tissue has relatively high levels of microsatellite instability, which would suggest an error in mismatch repair 
The com...
MGY 250 Unit 11 Quiz Questions with Correct Answers Latest Update 2025/2026
MGY 250 Unit 11 Quiz Questions with Correct Answers Latest Update 2025/2026 
The One Retinoblastoma World map is an excellent resource that "aims to connect affected families to expert care; promote evidence-based retinoblastoma treatment; and facilitate enhanced collaboration among treatment centers." In your web browser, go to the page 
 
Hint: you should be able to see them on the map, but this is a lot easier if you unclick "Retinoblastoma Treatment Centers" and "Stories" 
...
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MGY 250 Unit 11 Quiz Questions with Correct Answers Latest Update 2025/2026 
The One Retinoblastoma World map is an excellent resource that "aims to connect affected families to expert care; promote evidence-based retinoblastoma treatment; and facilitate enhanced collaboration among treatment centers." In your web browser, go to the page 
 
Hint: you should be able to see them on the map, but this is a lot easier if you unclick "Retinoblastoma Treatment Centers" and "Stories" 
...
MGY 250 Unit 10 Quiz Questions with Correct Answers Latest Update 2025/2026
MGY 250 Unit 10 Quiz Questions with Correct Answers Latest Update 2025/2026 
Why is genetic counselling important? (select all that apply) 
 
Can improve understanding of the cause of a disease 
Provides more information for treatment options 
Testing to 'rule in' or 'rule out' a diagnosis 
Provides recommendations about whether to have children - Answers Can improve understanding of the cause of a disease 
Provides more information for treatment options 
Testing to 'rule in' o...
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MGY 250 Unit 10 Quiz Questions with Correct Answers Latest Update 2025/2026 
Why is genetic counselling important? (select all that apply) 
 
Can improve understanding of the cause of a disease 
Provides more information for treatment options 
Testing to 'rule in' or 'rule out' a diagnosis 
Provides recommendations about whether to have children - Answers Can improve understanding of the cause of a disease 
Provides more information for treatment options 
Testing to 'rule in' o...
MGY 250 Unit 8 Quiz Questions and Answers Already Passed
MGY 250 Unit 8 Quiz Questions and Answers Already Passed 
Which of the following statements are true of the CRISPR system: (select all that apply) 
 
The CRISPR locus is easy to modify using RNA engineering and can be designed to cut any desired double stranded DNA sequence 
A bacterial CRISPR locus consists of repetitive sequences interspaced with viral DNA sequence 
The Cas9 enzyme recognizes DNA sequences using a guide RNA 
Both the CRISPR locus and 'cas' genes are part of a bacterial i...
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MGY 250 Unit 8 Quiz Questions and Answers Already Passed 
Which of the following statements are true of the CRISPR system: (select all that apply) 
 
The CRISPR locus is easy to modify using RNA engineering and can be designed to cut any desired double stranded DNA sequence 
A bacterial CRISPR locus consists of repetitive sequences interspaced with viral DNA sequence 
The Cas9 enzyme recognizes DNA sequences using a guide RNA 
Both the CRISPR locus and 'cas' genes are part of a bacterial i...
MGY 250 Unit 4 Quiz Questions with Verified Solutions Latest Update 2025/2026
MGY 250 Unit 4 Quiz Questions with Verified Solutions Latest Update 2025/2026 
Go to the OMIM website, (Links to an external site.) and look up Rett Syndrome, 312750, in the search bar. In the toolbar on the left, click on Population Genetics. What is the frequency of Rett syndrome in girls in metropolitan Tokyo? 
 
1/20,000 
1/200,000 
1/2,000 
1/200 - Answers 1/20,000 
The inheritance pattern of this pedigree is best described as (picture from quiz not included): 
 
X linked recessive 
Autoso...
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- • 6 pages •
MGY 250 Unit 4 Quiz Questions with Verified Solutions Latest Update 2025/2026 
Go to the OMIM website, (Links to an external site.) and look up Rett Syndrome, 312750, in the search bar. In the toolbar on the left, click on Population Genetics. What is the frequency of Rett syndrome in girls in metropolitan Tokyo? 
 
1/20,000 
1/200,000 
1/2,000 
1/200 - Answers 1/20,000 
The inheritance pattern of this pedigree is best described as (picture from quiz not included): 
 
X linked recessive 
Autoso...
MGY 250 Unit 2 Quiz Questions with Verified Solutions Latest Update 2025/2026
MGY 250 Unit 2 Quiz Questions with Verified Solutions Latest Update 2025/2026 
The most recent estimates indicate that the human genome has a total of ~58,000 genes, approximately subdivided into: 
 
~30,000 protein-coding genes, ~28,000 pseudogenes 
~20,000 protein-coding genes, ~10,000 lncRNAs, ~8000 sncRNAs, ~20,000 pseudogenes 
~58,000 protein-coding genes 
~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000 pseudogenes - Answers ~20,000 protein-coding genes, ~15,000 lncRNA...
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- • 6 pages •
MGY 250 Unit 2 Quiz Questions with Verified Solutions Latest Update 2025/2026 
The most recent estimates indicate that the human genome has a total of ~58,000 genes, approximately subdivided into: 
 
~30,000 protein-coding genes, ~28,000 pseudogenes 
~20,000 protein-coding genes, ~10,000 lncRNAs, ~8000 sncRNAs, ~20,000 pseudogenes 
~58,000 protein-coding genes 
~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000 pseudogenes - Answers ~20,000 protein-coding genes, ~15,000 lncRNA...
MGY250 Unit 5 - Complex Disorders Exam Questions with Correct Answers Latest Update 2025/2026
MGY250 Unit 5 - Complex Disorders Exam Questions with Correct Answers Latest Update 2025/2026 
Define case - Answers Affected individuals 
Define controls - Answers Non-affected individuals 
Case control studies - Answers Pair affected individuals with non-affected, matched according to environment exposure, occupation, geographical location. Ideally only difference should be disease presence. Compare extended families of both affected/non affected 
Odds ratio - Answers Odds individual with a sp...
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MGY250 Unit 5 - Complex Disorders Exam Questions with Correct Answers Latest Update 2025/2026 
Define case - Answers Affected individuals 
Define controls - Answers Non-affected individuals 
Case control studies - Answers Pair affected individuals with non-affected, matched according to environment exposure, occupation, geographical location. Ideally only difference should be disease presence. Compare extended families of both affected/non affected 
Odds ratio - Answers Odds individual with a sp...
MGY 250 Unit 1 - Perspectives on Medical Genetics Exam Questions with Correct Answers Latest Update 2025/2026
MGY 250 Unit 1 - Perspectives on Medical Genetics Exam Questions with Correct Answers Latest Update 2025/2026 
Describe how ethical guideliens for CRISPR have been developed - Answers Summit Dec 2015 in washington DC 
DNA Sequencing prep - Answers 1. Cut DNA into small pieces and insert into plasmid DNA for bacteria to replicate it 
2. Isolate DNA from bacteria and trasnsfer to plate 
3. Add free DNA bases, DNAP, primers and terminator bases 
Define hierarchical shotgun sequencing - Answers - Br...
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- • 2 pages •
MGY 250 Unit 1 - Perspectives on Medical Genetics Exam Questions with Correct Answers Latest Update 2025/2026 
Describe how ethical guideliens for CRISPR have been developed - Answers Summit Dec 2015 in washington DC 
DNA Sequencing prep - Answers 1. Cut DNA into small pieces and insert into plasmid DNA for bacteria to replicate it 
2. Isolate DNA from bacteria and trasnsfer to plate 
3. Add free DNA bases, DNAP, primers and terminator bases 
Define hierarchical shotgun sequencing - Answers - Br...
AMT 287 Final Exam Questions with Correct Answers Graded A+
LOG C3 - Transportation Exam Questions and Answers Latest Update 2025 Already Passed
VFIS Exam Questions and Answers Latest Update 2025
MGT8803 - Strategy Exam Questions and Correct Answers Latest Update 2024-2025 (Rated A+)
CCSVP Test Questions with Correct Answers Latest Update 2025-2026 Already Passed