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What is hemoglobin composed of? A. 4 heme, 4 iron, 4 globins B. 4 heme, 4 iron, 1 globin C. 2 heme, 2 iron, 2 globins D. 1 heme, 1 iron, 1 globin A. 4 heme, 4 iron, 4 globins What disorder does a defect in heme synthesis lead to? A. hemoglobinopathy B. coagulopathy C. thalassemia D. porphyria D. porphyria What is the function of the enzyme methemoglobin-cytochrome C reductase in red blood cell? A. to keep iron in the ferric state B. to keep iron in the ferrous sta...

What agency approves new test methodologies, instrument, and reagents before they are available for purchase by consumers Food and Drug Administration (FDA) How often should biological safety hoods be inspected annually What is the minimum number of standards required for a standard curve 3 What is the maximum magnification using a bright field microscope 1000X What is the most accurate pipette for reconstituting control material glass volumetric pipettes ...

Which of the following is not an external defense mechanism of natural immunity that provides the human body with a defense against invading microorganisms? Bursa of Fabricius All of the following are external defense mechanisms of natural immunity that provides the human body with a defense against invading microorganisms Skin, mucus, and body fluids Having an elevated temperature during an infection is an example of what type of immunity? Innate immunity Which defense m...

What agency approves new test methodologies, instruments, and reagents before they are available for purchase by consumers? FDA How often should biological safety hoods be inspected? Annually A chain of custody is required for all of the following: Legal blood alcohol, pre-employment drug screen, and paternity testing A chain of custody is required for all of the following, EXCEPT: Fetal fibronectin What federal legislation regulates most clinical laboratories? C...

This hormone is secreted by the anterior pituitary gland? Growth Hormone This hormone is stimulated by stress, exercise, hypoglycemia, testosterone, estrogen, and thyroxine (t4)? Growth Hormone This hormone promotes the growth in soft tissues, muscles, cartilage, and bone? Growth Hormone This hormone stimulates protein synthesis and fat/glucose metabolism? Growth Hormone An excessive amount of Growth Hormone causes what clinical condition in children? Gigantism ...

What is hemoglobin composed of? 4 heme, 4 iron, 4 globins What disorder does a defect in heme synthesis lead to? Porphyria Porphyria Deficiency in the enzymes of the porphyrin pathway leads to insufficient production of heme. The principal problem in these deficiencies is the accumulation of porphyrins, the heme precursors, which are toxic to tissue in high concentrations. What is methemoglobin? Methemoglobin is a form of hemoglobin that contains ferric [Fe3+] iron and h...

Concerning antigen-antibody reactions, the prozone effect causes which of the following results? A. False positive B. False negative C. No reaction D. Mixed field reaction B. False negative The following characteristics are applicable to Interferon-Gamma Release Assays (IGRAs) except: A. Can be used in patients with active tuberculosis disease symptoms B. Preferable for patients who have received a bacillus Calmette-Guérin (BCG) vaccination C. Can be used instead of purified ...

All of the following donors would be permanently deferred EXCEPT which one? 38-year-old male who received rabies vaccine after a dog bite 3 months ago All of the following donors would be permanently deferred: 75-year-old male who had acute hepatitis 20 years ago following surgery, 19-y/o first-time donor who received human growth hormone 12 years ago, and a 24-y/o donor with a history of a positive test for Hepatitis C from another blood center. What is the interval between bloo...

All of the following blood donors would be permanently deferred except which one? 38yr old male who received rabies vaccine after a dog bite 3mos ago What is the interval blood donations? 8 weeks The oral temperature of a donor must not exceed which value? 37.5C 99.5F What is the minimum acceptable hemoglobin for blood donors? 12.5 g/dL for allogeneic donors What is the lowest acceptable hematocrit for allogeneic blood donors? 38% What donor meets the requ...

After frozen RBC's have been thawed and washed, they must be used within how many hours? A. 6 B. 12 C. 24 D. 48 C. 24 What is the cause of neonatal alloimmune thrombocytopenia (NAIT)? A. Destruction of a neonate's platelets by alloantibodies crossing the placenta from the mother. B. Destruction of a neonate's platelets by an antibody that is produced by the neonate's own immune system. C. Decreased platelet production in the neonate. D. Destruction of a mother's platelet...

Which of the four elements in proteins differentiated this class of substances from carbohydrates and lipids? Nitrogen Which of the proteins is soluble in water? Albumin How are amino acids joined together to form a chainlike structure? Peptide bonding Proteins may become denatured when subjected to mechanical agitation, heat, or chemical treatment. What does denaturation of proteins refer to? Alteration of tertiary structure Which aminoacidopathy is NOT caused by...

Kills vegetative organisms but not all spores or viruses Boiling sterilization Used to sterilize media containing milk or serum;alternate heating Fractional sterilization Most effective method of sterilization Autoclaving What bacteria is used for quality control? Bacillus stearothermophilus What sterilization technique kills by oxidation? Dry heat What bacteria is used as a quality control for dry heat sterilization? Bacillus subtilis Cold sterili...

What term describes the morphology of organisms that vary in shape and size? Pleomorphic Capsules are the basis of which test? Serotyping A mucoid colony on blood agar medium indicates that which of the following characteristics may be present? Organism has a capsule. What are dark staining granules called? Metachromatic Which of the following organisms are non-motile? Shigella and Klebsiella In the bacterial growth cycle, growth ceases because nutrients a...

3 What is the minimum number of standards required for a standard curve? 1000X What is the maximum magnification using a brightfield microscope? Glass volumetric pipettes What is the most accurate pipette for reconstituting control material? Milli- Which unit of measure refers to 10^-3? 225/75= 3.00 What is the calculated cholesterol/HDL ratio given the following results? Cholesterol 225 mg/dL HDL 75 mg/dL 1:5 200 microliters of patient serum is diluted...

What agency approves new test methodologies, instruments and reagents before they are available for purchase by consumers? Food and Drug Administration (FDA) How often should biological safety hoods be inspected? annually What is the minimum number of standards required to form a standard curve? 3 What is the maximum magnification using a brightfield microscope? 1000X What is the most accurate pipette for reconstituting control material? glass volumetric pipettes...

Which if the following blood tests is used to diagnose gout? A. Alkaline phosphatase (ALP) B. Amylase C. Uric acid D. Creatinine C. Uric acid Select the equation which is used to determine the pH of a solution containing a weak acid and its salt. A. Van Deemter equation B. Van Slyke equation C. Nernst equation D. Henderson-Hasselbalch equation D. Henderson-Hasselbalch equation All of the following are directly involved in the production of semen EXCEPT? A. Prostate...

Specimens that can be analyzed for carbon dioxide 1. Serum 2. Plasma 3. Whole blood What will happen if blood is exposed to air during specimen collection for pH and blood gases? p C O 2 decreases Henderson-Hasselbalch equation p H = p k a + log salt / acid What is the ratio of bicarbonate:carbonic acid in normal plasma 20:1 Lab results on a known diabetic patient revealed a decreased bicarbonate and decreased ph. Which acid base disorder would most likely cause...

What consists of the gross renal anatomy? Kidneys, Ureters, Bladder, and Urethra What is the anatomy of the Nephron? Glomerulus. proximal convoluted tubule, descending Loop of Henle, Ascending Loop of Henle, distal convoluted tubule, and collecting duct. What are the 3 primary functions of the kidneys? Glomerulur Filtration, Tubular Reabsorption, and Tubular Secretion True or False: Cells are filtered through the glomerulus? False What is the GFR? Volume of blood...

What type of specimen is used for hematology testing? EDTA What type of specimen is used for coagulation testing? 3.2% citrated plasma When should a 3.2% citrated plasma be rejected? If the specimen is clotted, hemolyzed or QNS. How is platelet poor plasma obtained from a 3.2 citrated plasma specimen? By centrifuging the specimen. In a coagulation specimen, what is the ratio between anticoagulant and whole blood? 1:9 ratio In a coagulation specimen, what i...

What are four types of centrifuges commonly used in the clinical lab? Tabletop, Micro, High-Speed, and Ultra. What does the daily maintenance of a centrifuge commonly consist of? Cleaned with 10% bleach What does the periodic maintenance of a centrifuge commonly consist of? Speed check by tachometer What is the function of a centrifuge in the clinical lab? To separate substances based on density by centrifugal forces. What is the RCF formula? 1.118 -5 X 10 X r X ...