PKa Study guides, Class notes & Summaries

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MTM-Final Exam Basic Science Ionized forms like A- and BH+ are ________ and ______ diffusible across membrane water; poorly generic equation used to calculate week acidic and basic drugs 10 ^(pka-pH) = protonated/unprotonated equation to calculate weak acidic drugs 10^(pka-pH) = [nonionized(HA)]/[ionized(A-)] equation to calculate weak basic drugs 10^(pka-pH) = [ionized (BH+)]/[nonionized(B0] if the pka and pH difference is 1 or -1: ionization is 90% or 10% if the pka and pH differe...

Once a drug reaches its target it must (blank 1) the target and vice versa and then (blank 2) to begin the process of producing the desired biological effect correct answer: Blank 1: recognize Blank 2: bind Chemical structure on drug action correct answer: drug structure, ionization, lipophilicity, reactivity, metabolism Acid/Base properties of drugs correct answer: If pH< pKa then group is protonated form If pH>pKa then group is in unprotonated form Sulfonic Acid correct a...

The dipole moment in a water molecule Which statement about hydrogen bonds is NOT true? A) Hydrogen bonds account for the anomalously high boiling point of water. B) In liquid water, the average water molecule forms hydrogen bonds with three to four other water molecules. C) Individual hydrogen bonds are much weaker than covalent bonds. D) Individual hydrogen bonds in liquid water exist for many seconds and sometimes for minutes. E) The strength of a hydrogen bond depends on the linearit...

1. The pH of a solution of 0.0010 M NaOH is: A. 1 B. 11 C. 8 D. 0 E. 14 2. Water is a unique molecule which of the following contributes to water’s unique place in chemical world? The geometry of the molecule - The polarity of the O-H bonds - The ability of water molecules to hydrogen bond - The bond angle of water - All answers are correct 3. The bent shape of water is due to - The dipole arrows in a water molecule - The electronegativity different between hydrogen and oxygen ...

CIS 2200 Baruch Midterm Fich - Parupkar Jasuja Exam

NBME PHYSIOLOGY UPDATED EXAM WITH COMPLETE SOLUTIONS 2023/2024 Prostglandin - CORRECT ANSWER-From mast cells, macrophages, EC, and platelets Vasodilation, pain Rate controlling step in Insulin secretion - CORRECT ANSWER-Phosphorylation of glucose by glucokinase Glucokinase mutation - CORRECT ANSWER-Autosomal dominant form of early onset type 2 diabetes GLUT 2 - CORRECT ANSWER-low affinity high capacity glucose transporter. Uptake by beta cells Insulin release - CORRECT ANSWER-Bloo...

ACS BIOCHEMISTRY EXAM UPDATE 2023&2024 GRADED A+ 100% ACCURATE Henderson-Hasselbach Equation - ANSWER pH = pKa + log ([A-] / [HA]) FMOC Chemical Synthesis - ANSWER Used in synthesis of a growing amino acid chain to a polystyrene bead. FMOC is used as a protecting group on the N-terminus. Salting Out (Purification) - ANSWER Changes soluble protein to solid precipitate. Protein precipitates when the charges on the protein match the charges in the solution. Size-Exclusion Chromatography -...

Which AA likes to form alpha helix? correct answer: Glutamate Which AA likes to form beta sheet correct answer: Valine Which amino acids have aliphatic side chains? correct answer: alanine, glycine, valine, leucine, isoleucine, which amino acids have aliphatic hydroxyl side chains? correct answer: serine and threonine which amino acids have aromatic side chains? correct answer: phenylalanine, tyrosine, tryptophan which amino acids are sulfur containing? correct answer: cyste...

3800 Exam 3 PKAT Question and answers 100% correct 2024/2025What structure is the functional unit of the kidney? the neuron the acinus the nephron the ureter - correct answer the nephron Which two hormones are synthesized in the kidney? cortisol and epinephrine testosterone and estrogen aldosterone and cortisol erythropoietin and renin - correct answer erythropoietin and renin What is the end result of activation of the renin-angiotensin-aldosterone system? increase in blood...