Methylation Study guides, Class notes & Summaries

Angelman Syndrome causes (expression and % of total) correct answers **paternal imprinting defect, should be maternal expression 5-7 kb deletion on maternal chr15q11.2-13 (60-70%) UBE3A maternal deletion (11%) Paternal UPD15 (3-7%) Angelman testing strategy and condition features correct answers methylation first since finds ~80% of cases then UBE3A seq and del/dup features: happy demeanor, abnormal gait, seizures, delayed/absent speech Prader-Willi Syndrome causes (expression and...

USMLE Step 1- Biochemistry Exam Questions & Answers 2023/2024 Histones are rich in which 2 amino acids? - ANSWER-Lysine Arginine What histone protein is responsible for binding to the nucleosome and to the "linker" DNA thereby stabilizing the chromatin fiber? - ANSWER-H1 When does DNA and histone synthesis occur in the cell cycle? - ANSWER-S-phase Will the following be increased or decreased or neutral in heterochromatin? methylation acetylation - ANSWER-methylation increased ...

WGU Biochemistry OA (Latest 2022/2023) Verified Answers Bohr Effect chart (low pH) C- High CO2 H- High H+ A- Acidic R-Release of O2(rt. Shift) T- tense state (in tissues) Primary structure Sequence of amino acids that make up a protein Secondary Structure Sequence of amino acids fold. Tertiary Structure -more folding in a 3D shape. -R groups (side chains) Quaternary Structure Protein has more than 1 polypeptide chain. Chemical reaction -absorb and release en...

The tryptophan operon is a repressible operon that is: - ANSWER-Turned off whenever tryptophan is added to the growth medium. The lactose operon is likely to be transcribed when: - ANSWER-The cyclic AMP and lactose levels are both high within the cell. For a repressible operon to be transcribed, which of the following must occur? - ANSWER-RNA polymerase must bind to the promoter, and the repressor must be inactive. Which of the following, when taken up by the cell, binds to the represso...

ASCP MB: Extra-Practice Questions & Answers 2024 The Klenow fragment of E. coli DNA polymerase I is used: - ANSWER-to label DNA probes by random primer labeling. What is a solution hybridization method for the detection of nucleic acid:protein interactions? - ANSWER-gel mobility shift assay _____ involves mixing a labeled oligonucleotide with a protein extract to see if a specific interaction occurs, visible with an apparent increase in molecular size on a gel due to the protein:nucle...

CBSE FINAL EXAM 2023/2024 GRADED A LATEST VERSION A 66-year-old woman comes to the physician because of severe lower back pain. She is otherwise healthy with well-controlled hypertension and hyperlipidemia. She does not drink, but has smoked one pack of cigarettes per day for the past 20 years. An x-ray of the lumbar spine shows an anterior wedge compression fracture of L1. Results of dual-energy X-ray absorptiometry (DEXA) scan shows substantially decreased bone density in the region...

USMLE Step 1- Biochemistry Questions and Answers(2022)Answered test Histones are rich in which 2 amino acids? Ans- Lysine Arginine What histone protein is responsible for binding to the nucleosome and to the "linker" DNA thereby stabilizing the chromatin fiber? Ans- H1 When does DNA and histone synthesis occur in the cell cycle? Ans- S-phase Will the following be increased or decreased or neutral in heterochromatin? methylation acetylation Ans- methylation increased acety...

USMLE Biochemistry Exam Questions with Correct Answers Heterochromatin - ANSWER Highly Condensed DNA Transcriptionally inactive Ex. Barr bodies (inactivated X chromosomes) Euchromatin - ANSWER Less condensed DNA Transcriptionally active DNA Methylation - ANSWER Occurs at *CpG Islands* to repress transcription 'CpG Methylation Makes DNA MUTE' Template strand *cytosine* and *adenine* are methylated, which allow mismatch repair enzymes to distingu...

1. which of the following statements about chickens is false? a- all chickens perceive danger equally b-genetics pre-determines how a chicken responds to danger c-a stress resilient chicken is able to recover from danger and remain healthy d-all of the above ANS: a 2. which of the following could contribute to variation in the stress response of lambs at weaning? a-methylation of the glucocorticoid receptor gene b-polymorphisms in the melancortin 2 receptor gene c-polymorphisms in the nic...

NR507 Midterm Test Questions with Complete Solutions What is epigenetics? - ANSWER The study of heritable changes in gene expression or phenotype casued by mechanisms *other* than changes in DNA sequences. DNA methylation - ANSWER The attachment of a methyl group to a cytosine base is followed by a guanine base...causes a gene to become transcriptionally inactive or silent. Epigenetic processes play a major role in cancer initiation, progression, and treatmen...