- Study guides, Class notes & Summaries

Beractant (Survanta) Calfactant (Infasurf) Proactant alfa (Curosurf) Lucinactant (Surfaxin) - correct answersTypes of Exogenous Surfactants that have been approved for clinical use in the United States Survanta, Curosurf, Infasurf - correct answersTypes of Natural Surfactants Surfaxin - correct answersType of Synthetic Surfactant Prophylactic therapy of premature infants less than 1250 g birth weight or evidence child is at risk of RDS. Rescue treatment of infants with evidence of R...

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2 pages

Written in 2025/2026

Grade A+

RealGrades

Definition of detergent - correct answers A surface-active agent that reduces surface tension Definition of surface tension - correct answers Force causesd by attraction between like molecules that occurs at liquid-gas interfaces and holds liquid surface in tact Clinical indications for surfactant administration - correct answers Treatment or prevention of RDS in newborns - Prophylactic treatment - Rescue treatment Composition of pulmonary surfactant - correct answers Lipids: 85-90% ...

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2 pages

Written in 2025/2026

Grade A+

RealGrades

Another name for surface-active agents is - correct answers Detergent As it relates to an alveolus, LaPlace's law is written as - correct answers Pressure = (2 * surface tension)/radius Lack of pulmonary surfactant in respiratory distress syndrome (RDS) of the newborn typically results in - correct answersHigh surface tension The term used to describe surfactant produced outside of the patient's body is - correct answers Exogenous Endogenous surfactant is produced by - correct ...

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5 pages

Written in 2025/2026

Grade A+

RealGrades

1. What is/are the most abudant component of surfactant? A. Dipalmitoylphosphatidylcholine (DPPC) B. Surfactant protein B C. SP-C D. Phosphatidylglycerol - correct answersA. Dipalmitoylphosphatidylcholine (DPPC) Rationale: Phosphatidylcholine (PC) is the most abundant phospholipid (85%) and is mostly saturated (40% to 55%) in the form of dipalmitoylphosphatidylcholine (DPPC), the most important surfactant component in reducing surface tension. 2. Surfactant inactivation and dysfunction...

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4 pages

Written in 2025/2026

Grade A+

RealGrades

Beractant - correct answers Survanta® A modified natural surfactant (bovine) -SP-B/SP-C + DPPC, Palmitic acid, Tripalmitin Indications for use -Prophylactic therapy of premature infants less than 1250 g birth weight or with evidence of surfactant deficiency and risk of RDS; the agent should be given within 15 minutes of birth or as soon as possible -Rescue treatment of infants with evidence of RDS; the agent should be given within 8 hours of age Beractant (Survanta®) Dosage -100 mg...

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2 pages

Written in 2025/2026

Grade A+

RealGrades

Muculytic Generic Name: Dornase alfa - correct answers Trade Name: Pulmozyme Type of route Dornase alfa use? - correct answers SVN Standard dose and solution strenght of Dornase alfa? - correct answers2.5 mg in a 2.5 solution Frequency (hr) or Dornase alfa? - correct answers24 hr Mucolytic Generic Name: n-acetylycsteine - correct answers Trade Name: Mucomyst, Mucosol Type of route n-acetylcysteine use? - correct answers SVN Standard dose & solution strength of n-acetycysteine...

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3 pages

Written in 2025/2026

Grade A+

RealGrades

After assisting with administration of calfactant for prophylaxis of respiratory distress syndrome to a 26-week-old infant weighing 1100 g, the infant's pulmonary function appears to be improving. Which of the following should you avoid within the first hour after administration? A. Decrease the oxygen requirements B. Extubate the patient C. Suction the patient D. All of these are correct. - correct answers Suction the patient You are working in the neonatal intensive care unit. You ...

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20 pages

Written in 2025/2026

Grade A+

RealGrades

After assisting with administration of calfactant for prophylaxis of respiratory distress syndrome to a 26-week-old infant weighing 1100 g, the infant's pulmonary function appears to be improving. Which of the following should you avoid within the first hour after administration? A. Decrease the oxygen requirements B. Extubate the patient C. Suction the patient D. All of these are correct. - correct answers Suction the patient You are working in the neonatal intensive care unit. You ...

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6 pages

Written in 2025/2026

Grade A+

RealGrades

Beractant - correct answers Brand name: Survanta Class: surfactant Mode of action: prophylactic therapy Purpose: for premature infants weighing less than 1250g OR with evidence of surfactant deficiency/at risk for RDS At risk: given 15 min of birth rescue treatment: within 8 hours of birth Administration: warm it to body temperature. instilled into trachea with ETT. Calfactant - correct answers Brand name: Infasurf Class: surfactant Mode of action: prophylaxis (prevention of RDS) Pu...

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2 pages

Written in 2025/2026

Grade A+

RealGrades

No because the proper gestational term for surfactant is 24-29 weeks - correct answers Would you give surfactant to a 36 week old gestational aged newborn who shows no signs of respiratory distress and has stable vitals? Surfactant agents - correct answers Surface active agents that lower surface tension? Detergent - correct answers Another name for surface active agents is? Surface tension - correct answers Force caused by attraction between like molecules that occurs at liquid-gas int...

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3 pages

Written in 2025/2026

Grade A+

RealGrades

Surfactant is already in your ______? - correct answers lungs When you inhale, a stretch response occurs, and ___________ that hold surfactant secrete surfactant into the ________? - correct answers lamellar bodies, alveolus The constant secretion of surfactant is balanced by? - correct answers during exhalation, old surfactant is squeezed out and new surfactant is added on inspiration. 90-95% of surfactant is taken back up and recycled by type II cells. __________ are not born with eno...

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5 pages

Written in 2025/2026

Grade A+

RealGrades

After assisting with administration of calfactant for prophylaxis of respiratory distress syndrome to a 26-week-old infant weighing 1100 g, the infant's pulmonary function appears to be improving. Which of the following should you avoid within the first hour after administration? All of these are correct. Decrease the oxygen requirements Suction the patient Extubate the patient - correct answers Suction the patient An infant delivered at 29 weeks' develops respiratory distres...

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19 pages

Written in 2025/2026

Grade A+

RealGrades

A surface active agent designed to lower surface tension is called? - correct answers Exogenous Surfactant why is Laplace's Law different in the alveoli - correct answers b/c there is only a single air-liquid interface Beractant - correct answers Survanta 4ml and 8ml initial dose: 4ml/kg Calfactant - correct answers Infasurf 3ml and 6ml initial dose: 3ml/kg Poractant Alfa - correct answers Curosurf 1.5 ml initial dose: 2.5 ml/kg Lucinactant - correct answers ...

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11 pages

Written in 2025/2026

Grade A+

RealGrades

Suppose that your roommate is taking the same class you are and wants to beat you on an exam in order to help their ranking in the class, which, they believe, will help their grade in the class, which, they believe, will help them get into a better law school. They realize that they could lock you in the bathroom so you'd miss the exam, which they figure will hurt your grade. Give three reasons that support the claim that it would be morally impermissible for your roommate to lock you in the ...

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7 pages

Written in 2025/2026

Grade A+

RealGrades

Which of the following is the appropriate dose of beractant (Survanta)? - correct answers4 mL/kg divided in 4 doses Which of the following pairs of generic and brand names for surfactant replacement therapies is correct? - correct answers Poractant alfa: Curosurf Which of the following should never be done with natural surfactant replacements? - correct answers Warm the suspension using an artificial warming device An infant delivered at 29 weeks' develops respiratory distress, has ...

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10 pages

Written in 2025/2026

Grade A+

RealGrades

1. another name for surface active agents is a. mucolytic b. detergent c. bronchodilator d. antibiotic - correct answers detergent 2. as it relates to an alveolus, laplace's law is written as a. pressure=(4 x surface tension)/radius b. dyn/cm c. pressure=surface tension/radius d. pressure=(2 x tension)/radius - correct answers pressure=(2 x tension)/radius 3. lack of pulmonary surfactant in respiratory distress syndrome(RDS) of the newborn typically results in a. high surface t...

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14 pages

Written in 2025/2026

Grade A+

RealGrades

Antitussives - correct answers Codeine (generic only) Hydrocodone *Dextromethorphan Topical Nasal Decongestants - correct answers Oxymetazoline (Afrin, and others) Phenylephrine (Sudafed PE, Coricidin, some triaminics) *Tetrahydrozoline (Tyzine, Visine) Xylometazoline (Otrivin) Oral Decongestants - correct answers*Pseudoephedrine (Triaminic Allergy Congestion, and many combination products, look for "D") Phenylephrine Topical Nasal Steroid Decongestants - correct answers*F...

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3 pages

Written in 2025/2026

Grade A+

RealGrades

What is Surfaxin? - correct answers A surfactant proposed by Discovery Labs. What is the AZT trial? - correct answers No information provided. What is the purpose of the Surfaxin trial in Bolivia? - correct answers To test its effectiveness in treating RDS in infants. What percentage of neonatal deaths in Bolivia is caused by RDS? - correct answers30-50%. How many approved surfactants are there in the U.S.? - correct answers4. Why are the approved surfactants not available in Boli...

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3 pages

Written in 2025/2026

Grade A+

RealGrades