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NPLEX 2 Pharm Questions and Answers well Explained Latest 2024/2025 Update 100% Correct.
Acyclovir - ANTIVIRAL (Inhibits DNA polymerase) 
IND: 
- HSV ixn and prevention, VZV, EBV, disseminated neonatal herpes, CMV ixn 
ACT: 
- Nucleoside analog inhibiting viral replication, NON-CURATIVE 
A/E: 
- HA, diarrhea, nausea, delirium, tremor, Htn, transent renal dysfunction w/ high doses, encephalopathy 
(IV), CAN PROMOTE EMERGENCE OF RESISTANT STRAINS 
C/I: 
- Preg C 
INT: 
- Synergistic toxicity w/ ZIDOVUDINE (AZT). 
MONITOR: urinalysis, BUN, serum creatinine, LV enz, CBC 
Rx: Oral, topic...
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