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Exam (elaborations)
CHEM 441PROBLEM SET 2 BIOCHEMISTRY . (A+ GRADED)
Increasing concentrations of either 2,3-bisphosphoglycerate (BPG) 
or protons (H+) cause a ____________ (rightward OR leftward) shift 
of the hemoglobin/oxygen binding curve. However, the mechanisms 
by which these two substances mediate this effect are distinct. 
Compare & contrast the way by which BPG and protons interact 
with hemoglobin and thereby influence its structure and 
function. Please be specific. 
Selected 
Answer: 
1.) Rightward 
2.) Only one BPG molecule can interact with hemoglo...