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ACAAI Biologic Maylene Xie Questions and certified answers 2023/2024
ACAAI Biologic Maylene Xie Questions and certified answers 2023/2024 
 
Which of the following is incorrectly paired? 
a) adalimumab - human synthetic 
b) rituximab - humanized 
c) infliximab - chimeric 
d) omalizumab - humanized - correct answer B. Rituximab is a chimeric ab, not humanized. The substem -xi- denotes chimeric, similar to infliximab. 
 
Adalimumab (Humira) is the first fully human synthetic antibody to be developed using phage technology. 
 
Omalizumab is humanized, meaning the co...
Exam (elaborations)
ACAAI Early Phase Response Questions and correct answers 2023/2024
ACAAI Early Phase Response Questions and correct answers 2023/2024 
 
Early-phase mechanisms are allergen-induced mast cell secretion of histamine, prostaglandins, and leukotrienes; late-phase mechanisms are eosinophil chemotaxis, caused by chemical mediators produced in the early reaction - correct answer What are the primary mechanisms of early- and late-phase allergic rhinitis? 
 
They block both the early-phase (rhinorrhea, sneezing) and late-phase (congestion) responses - correct answer Int...
Exam (elaborations)
ACAAI Extensive Questions and Answers 20232024 (Comprehensive Chapters)
ACAAI Extensive Questions and Answers (Comprehensive Chapters) 
 
Small-molecule antigen requires covalent linkage to a larger carrier to stimulate adaptive immune response. The process is achieved in collaboration between hapten-specific B cells and carrier-specific T cells. This is the basis of developing conjugated vaccines. - correct answer What is the hapten-carrier effect? 
 
SEB and SEC from Staphylococcus aureus cause food poisoning. TSST from Staphylococcus aureus and SPE-C from Strept...
Exam (elaborations)
ACAAI Food Allergy Questions and 100% correct answers 2023/2024
ACAAI Food Allergy Questions and 100% correct answers 2023/2024 
 
 
the food allergy epidemic - correct answer - 32 million americans 
- 1 in 10 adults, 1 in 13 children (based on symptoms) 
- 42% children, 51% adults = anaphylaxis 
- higher number of children in lower age groups have allergies, but they outgrow it 
 
food allergy - correct answer an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food 
 
adverse food reactions (no...
Exam (elaborations)
ACAAI immune system Cells Questions and correct answers 2023/2024
ACAAI immune system Cells Questions and correct answers 2023/2024 
 
Uncontrolled activation of macrophages with a marked increase in circulating cytokines is called - correct answer hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome, when secondary to chronic rheumatoid disease. 
 
This potentially life-threatening syndrome is characterized by high fever, hepatosplenomegaly, high ferritin and triglyceride levels, and low fibrinogen and circulating NK levels. Hemophagocyt...
Exam (elaborations)
ACAAI Reaction Phases Questions and verified answers 2023/2024
ACAAI Reaction Phases Questions and verified answers 2023/2024 
 
Histamine, tryptase, chymase & carboxypeptidase - correct answer Name 4 important mediators involved in an early phase reaction? 
 
Dust mite, cockroach - correct answer Testing for which allergens may come back positive in patients with shellfish allergy? 
 
1mg/mL - correct answer What is the highest concentration of venom intradermal skin tests? 
 
An increase in FEV1 of 12% and ≥200 mL - correct answer What constitutes a sig...
Exam (elaborations)
ACCAI Allergic Questions and answers 2023/2024
ACCAI Allergic Questions and answers 2023/2024 
 
1. D, pg.757 Both methacholine and histamine are considered direct-acting constrictors in bronchial challenges. Indirect acting constrictors include mannitol, adenosine, exercise, and cold air. There is little difference between the use of histamine and methacholine; however, methacholine is used more widely due to fewer side effects. One disadvantage of the direct acting constrictors is that they produce positive tests for patients with asthma a...
Exam (elaborations)
ACCAI Skin Tests Questions and ready answers 2023/2024
ACCAI Skin Tests Questions and ready answers 2023/2024 
 
A 32 year old patient with history of HIV, severe eczema, and severe asthma on chronic prednisone therapy receives a TB skin test (DTH). 72 hours later, the induration is less than 5mm. His most recent CD4 count was 600. Which of the following is NOT a possible explanation for why his induration is less than 5mm. 
a) eczema 
b) lack of prior exposure to TB 
c) steroid therapy 
d) HIV 
e) occult cancer - correct answer D. Anergy is presen...
Package deal
2020 AAAAI ACAAI Online Joint Board Certificatio PACKAGE
2020 AAAAI ACAAI Online Joint Board Certificatio PACKAGE
Exam (elaborations)
AAAAI ACAAI Online Joint Board Certification Review Questions & Detailed Answers 2024
AAAAI ACAAI Online Joint Board Certification Review Questions & Detailed Answers 2024
Exam (elaborations)
ACAAI board review allergens
ACAAI board review allergens
Exam (elaborations)
ACAAI board review cells in immune system
ACAAI board review cells in immune system
Exam (elaborations)
ACAAI FIT Corner Questions
ACAAI FIT Corner Questions
Exam (elaborations)
ACAAI Review 4th Edition - ALL CHAPTERS
ACAAI Review 4th Edition - ALL CHAPTERS
Exam (elaborations)
ACAAI Review 4th Edition - Chapter 1
ACAAI Review 4th Edition - Chapter 1
Exam (elaborations)
ACAAI Review 4th Edition - Chapter 7
ACAAI Review 4th Edition - Chapter 7
Exam (elaborations)
ACAAI Review 4th Edition - Chapter 8
ACAAI Review 4th Edition - Chapter 8
Exam (elaborations)
ACAAI Review CHAPTER 5
ACAAI Review CHAPTER 5
Exam (elaborations)
ACAAI Review CHAPTER 9
ACAAI Review CHAPTER 9
Exam (elaborations)
Allergy FIT Board Review Middleton 8th
Allergy FIT Board Review Middleton 8th