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Exam (elaborations)
ABFM HEART FAILURE PATHOPHYSIOLOGY SUMMARY 2024
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8
January 2024
2023/2024
A+
1. Post MI remodeling: Postinfarction remodeling divided into 2 phases:
a. early phase (wi 72 hrs):
i. expansion of infarct zone, resulting in wall thinning, ventricular dilatation diastolic & systolic wall stresses.
ii. activation renin-angiotensin system
iii. production of atrial & brain natriuretic peptides (ANP & BNP).
b. late phase (> 72 hrs). involves LV more globally w time-dependent dilatation, distortion of ventricular shape, mural hypertrophy (an adaptive response) to offset ...
TUTORNELSON
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