NURSING NUR 323 (NURSING NUR 323)
Miami University Of Ohio
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Hesi Guide - Pharmacology
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---35August 20212021/2022
- 6) ACE inhibitors-(-pril ending, such as lisinopril) o Blocks conversion of angiotensin 1 to angiotensin 2 and as a 
result, aldosterone is not released. 
§ Lower aldosterone means more sodium will be excreted and potassium will be retained 
§ There is no vasoconstriction from angiotensin 2 either. 
o First line drug for pts with (compensated) heart failure – ACE inhibitors prevent remodeling 
of the heart (the enlarged heart with decreased contractility). Breaks the RAA system. 
o If you us...
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