Pharmacology
Johns Hopkins University School Of Medicine
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Essay
Paroxetine’s Pharmacokinetic and Pharmacodynamic Factors
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---4December 20222021/2022A+
- Paroxetine is characterized as an antidepressant whose properties are induced by selective inhibition of serotonin uptake. The phenylpiperidine (trans-isomeric) has a low affinity for receptors – muscarinic receptors – translating to non-direct interaction with monoamine receptors which are also neurotransmitters. Paroxetine is actively absorbed in the gastrointestinal tract and undergoes a first pass metabolism leading to its reduced bioavailability. After transformation (in the liver), par...
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Exam (elaborations)
ATI PN Pharmacology Review 75 Questions with Answers. Graded A
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---15September 20212021/2022A+
- 1. After instilling an eye drop that has a systematic effect, the nurse should press on which of the 
following to prevent absorption into the circulation? 
a. The bony orbit 
b. The nasolacrimal duct 
c. The conjunctival sac 
d. The outer cantus of the eye 
2. A nurse is caring for a client who has just been diagnosed with primary open-angle glaucoma 
(POAG) during a screening examination. Which of the following data collection finding should the 
nurse expect? 
a. Sudden loss of central vis...
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