Pharmacology

Johns Hopkins University School Of Medicine

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Paroxetine’s Pharmacokinetic and Pharmacodynamic Factors
  • Essay

    Paroxetine’s Pharmacokinetic and Pharmacodynamic Factors

  • Paroxetine is characterized as an antidepressant whose properties are induced by selective inhibition of serotonin uptake. The phenylpiperidine (trans-isomeric) has a low affinity for receptors – muscarinic receptors – translating to non-direct interaction with monoamine receptors which are also neurotransmitters. Paroxetine is actively absorbed in the gastrointestinal tract and undergoes a first pass metabolism leading to its reduced bioavailability. After transformation (in the liver), par...
  • TutorAplus
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 ATI PN Pharmacology Review 75 Questions with Answers. Graded A
  • Exam (elaborations)

    ATI PN Pharmacology Review 75 Questions with Answers. Graded A

  • 1. After instilling an eye drop that has a systematic effect, the nurse should press on which of the following to prevent absorption into the circulation? a. The bony orbit b. The nasolacrimal duct c. The conjunctival sac d. The outer cantus of the eye 2. A nurse is caring for a client who has just been diagnosed with primary open-angle glaucoma (POAG) during a screening examination. Which of the following data collection finding should the nurse expect? a. Sudden loss of central vis...
  • NURSEROSE
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