QUESTIONS AND ANSWERS

Prodrug - ANSWER-An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability - ANSWER-the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemical stability, solubility, and first pass

Pharmacokinetics - ANSWER-Involves ADME (absorption, distribution, metabolism and elimination). Absorption: absorption from the administration site either directly or indirectly into the blood/plasma. Distribution: reversibly or irreversibly move from the bloodstream into the interstitial and intracellular fluid. Metabolism: bio-transformed via hepatic metabolism or by other tissues. Elimination: lastly, the drug & its metabolites are eliminated from the body The route of administ...

NUR 641E Final Exam 2023 - Advanced Pathophysiology and Pharmacology for the Nurse Educator Exam Graded A+ Pharmacokinetics - ANSWER-Involves ADME (absorption, distribution, metabolism and elimination). Absorption: absorption from the administration site either directly or indirectly into the blood/plasma. Distribution: reversibly or irreversibly move from the bloodstream into the interstitial and intracellular fluid. Metabolism: bio-transformed via hepatic metabolism or by other tissu...

NUR 641E Midterm Exam Study Guide 2023 Graded A+ Prodrug - ANSWER-An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability - ANSWER-the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemi...

NUR 641 FINAL EXAM With Complete Solution ( ALL Correct Question And Answers ) LATEST 2021/2021 NUR 641 FINAL EXAM QUESTION AND ANSWERS 100% SATISFIED 1) Insulin is used to treat hyperkalemia because it A stimulates sodium to be removed from the cell in exchange for potassium B. Binds to potassium to remove it through the kidneys. C. transports potassium from the blood to the cell along with glucose D. Breaks down the chemical components of potassium , causing it to be no longer effecti...

Note: Read the questions: the questions only have one answer unless the question specifically states there is more than one correct answer. ANSWERED SO FAR Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. The liver is the principal site of drug metabolism. Although metabolism typically inactivates drugs, some drug metabolites are pharmacologically active—sometimes even more so than the parent compound. An inactive or weakl...

Understand what a prodrug is, and activation/inactivation by liver enzymes, and how it differs from active drugs. The liver is the principal site of drug metabolism. Although metabolism typically inactivates drugs, some drug metabolites are pharmacologically active—sometimes even more so than the parent compound. An inactive or weakly active substance that has an active metabolite is called a prodrug, especially if designed to deliver the active moiety more effectively. Know what Bioavailabil...