NR566 Week 5 Study Guide Chapter 18: Drugs Affecting the Hematopoietic System/NR566 Week 5 Study Guide Chapter 18: Drugs Affecting the Hematopoietic System/NR566 Week 5 Study Guide Chapter 18: Drugs Affecting the Hematopoietic System

NR 566 Week 4 Study Guide Chapter 25: Drugs Used in Treating Inflammatory Processes Pharmacodynamics: • MOA: exact MOA of NSAIDS is not known, thought to be inhibition of cyclo-oxygenase activity and prostaglandin synthesis o Inhibition of lipo-oxygenase, leukotriene synthesis, lysosomal enzyme release, neutrophil aggregation, and various cell membrane functions may also occur o May also suppress rheumatoid factor • Two cyclo-oxygenase isoenzymes have been identified: COX-1 and COX 2...

Exam (elaborations) NR566 / NR 566 (NR566) (NR566 / NR 566 (NR566)) NR566 Week 2 Study Outline NR566 Week 2 Study Outline Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios. Chapter 17: Drugs Affecting the Respiratory System • Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for: o o Short and long acting beta agonists Short-acting beta agonists , Albuterol (ProAir,...

NR566 Week 5 Study Outline Chapter 18: Drugs Affecting the Hematopoietic System • Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for: Anticoagulants • Pharmacodynamics • Oral anticoagulants such as warfarin (Coumadin) inhibit the hepatic synthesis of several clotting factors, including factor X. • Heparin inhibits the activity of several activated clotting factors by accelerating the activity of antithrombin III. ...

NR 566 Week 7 Study Guide Chapter 48: Women as Patients Pharmacokinetic gender differences between men and women • These three medications have shown differences that are clearly significant between men and women • Propranolol (Inderal): early drug that showed a clear gender difference in metabolism (clearance) o PO doses: significantly higher (63%) rate of clearance in men than women o IV doses do not do this: indicates hepatic first pass metabolism o Women: show a significantly grea...

NR566 Week 3 Study Outline Chapter 16: Drugs Affecting the Cardiovascular & Renal Systems Angiotensin converting enzyme inhibitors (ACEI or ACE Inhibitors) o Drugs: benazepril, captopril, enalapril, fosinopril, lisinopril, and moexipril, perindopril, quinapril, ramipril, trandolapril o Pharmacodynamics: o MOA: Slows or inhibits the angiotensin converting enzyme which then decrease how much angiotensin II (AT II) is produced thus lowering BP o Inhibit RAAS activity=decreased production of b...