NRNP 6566

NRNP 6566 MidtermStudy Guide NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as ...

NRNP 6566 Final Exam, NRNP 6566/ NRNP6566 Advanced Care of Adults in Acute Settings I, Questions and Verified Answers. 2023/ 2024 New Update- Walden University

NRNP 6566 Midterm Study. Guide NRNP 6566 MIDTERM EXAM LATEST QUESTIONS AND ANSWERS WEEK 1-5, NRNP 6566 NRNP6566 Advanced Care of Adults in Acute Settings I Walden University

NRNP 6566 WEEK 3 KNOWLEDGE CHECK Q&AS BEST EXAM SOLUTION LATEST DOWNLOADS 2022/2023

NRNP 6566 WK1-5 Midterm Exam With Complete Solution Graded A+ Describe cytochrome p450 system - Answer Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors - Answer block metabolic activity from one or more CYP450 enzymes Inducers - Answer increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound - Answer Albumin is the plasma prot...

1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. a. Cytochrome p450 system is a series of enzymes used to metabolize medications. b. Drugs that cause CYP450 metabolic drug interactions are referred to as either inhibitors or inducers. Inducers increase CYP450 enzyme activity by increasing enzyme synthesis c. Inhibitors block the metabolic activity of one or more CYP450 enzymes 2. De...

NRNP 6566 week 1 to 5 Key Concepts. NRNP 6566 Key Concepts Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. a. Cytochrome p450 system is a series of enzymes used to metabolize medications. b. Drugs that cause CYP450 metabolic drug interactions are referred to as either inhibitors or inducers. Inducers increase CYP450 enzyme activity by increasing enzyme synth...

NRNP 6566 WK1-5 Midterm Exam Describe cytochrome p450 system Ans- Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors Ans- block metabolic activity from one or more CYP450 enzymes Inducers Ans- increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound Ans- Albumin is the plasma protein with the greatest capacity for binding drugs...

NRNP 6566 WK 10 Knowledge Check. A 57 year old female is admitted to the oncology unit for chemotherapy related to her to acute leukemia. Her initial dose of chemo was 2 days ago. While rounding today, the patients tells the NP that she feels so weak. The NP notes her heart rate is 44 today (down from 68 2 days ago). She has had less than 100 cc of urine out over the last 24 hours. Labs from this morning include: LAB DATA: -Sodium 131 -Potassium 7.8 -Chloride 105 -Bicarbonate 1...

NRNP 6566 week 6 knowledge check. A 54 year old female has a 30 year pack smoking history. She recently underwent pulmonary function testing which showed moderate obstructive lung disease. What would your treatment plan (including medications) include for this patient? Correct Answer: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 suggests that smoking cessation should be immediately pursued if the patient is still smoking. Nicotine replacement (gum, inhal...

NRNP 6566 Week 5 Knowledge Check QUESTION 1 1. A 54-year women is 3 days post abdominal surgery for removal of a cancerous mass in her abdomen. She develops acute shortness of breath associated with tachycardia and hypotension. CT Scan of the chest is positive for multiple small pulmonary embolism. What medication and dosing would you order initially to treat the pulmonary embolism? This patient should be given fondaparinuc (Arixtra) subcutaneously. Dosing is weight- based: 1. 5 mg SQ on...

NRNP 6566Week 4 knowledge check. A 47 year old male admitted with an infected elbow wound. On his second day in the hospital you find him in his room confused and agitated. Vital signs are as follows: Temperature – 96.2 °F Pulse -140 beats per minute Respirations – 40 breaths per minute Blood Pressure – 90/40 mmHg Labs include a WBC count of 3,000 Pt weighs 185 pounds Further assessment of him includes: Urine output of 100cc for the last 8 hours Pulse oximetry of 88% o...

NRNP 6566 Knowledge Check Week 3 Amiodarone has possible complex interactions with multiple medications. It has an effect on warfarin metabolism. Amiodarone is a potent inhibitor of cytochrome P450 enzymes and inhibition of these enzymes will cause an increased plasma concentration and decreased clearance; thereby increasing the prothrombin time and INR placing the patient at increased risk for bleeding complications. Hence, when given together, warfarin dose should be decreased and frequent...

NRNP 6566 week 11 knowledge check How would you differentiate between diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic syndrome (HHS)? Correct Answer: Both of these conditions will include high levels of blood glucose readings. DKA will exhibit acidosis and urinary ketones while HHS will not. Treatment for each condition is similar with fluid bolus and infusion as well as insulin bolus and infusion. Juan is a 42 year old male with complaints of nausea and vomiting for...

NRNP 6566 final prep 6-12 Normal pH 7.35-7.45 <7.35 Acid >7.45 alkalosis respiratory aklalosis pH> 7.45, PaC02 low, HC03 low respiratory acidosis pH < 7.35 PaCO2 > 45 Hc03 normal 22-26 Metabolic alkalosis pH > 7.45 HCO3 > 26 PaC02 45-35 normal oxygen levle 80-100 mild hypoxemia 60-80 moderate hypoxemia 40-60 severe hypoxemia <40 A-a gradiatian calculation is a calculation of what? level of hypoxia PA02-Pa02 A-a gradiant varies with age, calcula...

NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone synthesis and br...

NRNP 6566 Knowledge Check Week 3 Amiodarone has possible complex interactions with multiple medications. It has an effect on warfarin metabolism. Amiodarone is a potent inhibitor of cytochrome P450 enzymes and inhibition of these enzymes will cause an increased plasma concentration and decreased clearance; thereby increasing the prothrombin time and INR placing the patient at increased risk for bleeding complications. Hence, when given together, warfarin dose should be decreased and frequent...

• NRNP 6566 Week 4 knowledge check A 47 year old male admitted with an infected elbow wound. On his second day in the hospital you find him in his room confused and agitated. Vital signs are as follows: Temperature – 96.2 °F Pulse -140 beats per minute Respirations – 40 breaths per minute Blood Pressure – 90/40 mmHg Labs include a WBC count of 3,000 Pt weighs 185 pounds Further assessment of him includes: Urine output of 100cc for the last 8 hours Pulse oximetry of...

NRNP 6566 Week 5 Knowledge Check QUESTION 1 1. A 54-year women is 3 days post abdominal surgery for removal of a cancerous mass in her abdomen. She develops acute shortness of breath associated with tachycardia and hypotension. CT Scan of the chest is positive for multiple small pulmonary embolism. What medication and dosing would you order initially to treat the pulmonary embolism? This patient should be given fondaparinuc (Arixtra) subcutaneously. Dosing is weight- based: 1. 5 mg SQ on...

• NRNP 6566 week 6 knowledge check. A 54 year old female has a 30 year pack smoking history. She recently underwent pulmonary function testing which showed moderate obstructive lung disease. What would your treatment plan (including medications) include for this patient? Correct Answer: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 suggests that smoking cessation should be immediately pursued if the patient is still smoking. Nicotine replacement (gum,...