PHARM NR566 NR566 Final Exam Study Guide.

Complete the following table to study/prepare for the treatment of STIs/STDs according to National STD curriculum completed in Week 5 of the course. STI/STD First line drug, dose, route, frequency Chlamydia (Among Adolescents and Adults) Azithromycin, 1 g PO once or Doxycycline, 100 mg PO 2 times/day × 7 days Uncomplicated gonococcal urethritis Ceftriaxone, 250 mg IM once, plus azithromycin, 1 g PO once Bacterial Vaginosis Metronidazole, 500 mg PO 2 times/day × 7 days or Metronidazole gel (0.75%), 1 full applicator (5 g) intravaginally once/day × 5 days or Clindamycin cream (2%), 1 full applicator (5 g) intravaginally at bedtime × 7 days Herpes Simplex Virus (First Clinical Episode) Acyclovir, 400 mg PO 3 times/day × 7–10 days (or longer) or Acyclovir, 200 mg PO 5 times/day × 7–10 days (or longer) or Famciclovir, 250 mg PO 3 times/day × 7–10 days (or longer) or Valacyclovir, 1 g PO 2 times/day × 7–10 days (or longer) Pelvic Inflammatory Disease (PID) (IM or Oral Regimens) Doxycycline (100 mg PO 2 times/day × 14 days), plus either cefoxitin (2 g IM once, boosted with probenecid 1 g PO once) or ceftriaxone (250 mg IM once), with or without metronidazole (500 mg PO 2 times/day × 14 days) Syphilis (Primary and Secondary) Benzathine penicillin G, 2.4 million units IM once  Doxazosin o Side Effects orthostatic hypotension, reflex tachycardia, and nasal congestion  Dutasteride o Patient teaching and response to delayed onset of therapeutic effect extremely long half-life (about 5 weeks); therefore it takes months to clear the