Medical Notes

Neuromuscular junction (NMJ) disorders result from destruction, malfunction, or absence of one or more key proteins involved in neuromuscular transmission, illustrated diagrammatically in fig 1. The most common pathology is antibody-mediated damage or downregulation of ion channels or receptors, resulting in myasthenia gravis (MG), Lambert-Eaton myasthenic syndrome (LEMS), and acquired neuromyotonia (Isaac’s syndrome). ...

Detailed Title of the topic 1. General Pharmacology a) Introduction, definitions and scope of pharmacology b) Routes of administration of drugs c) Pharmacokinetics (absorption, distribution, metabolism and excretion) d) Pharmacodynamics e) Factors modifying drug effects f) Drug toxicity - Acute, sub- acute and chronic toxicity. g) Pre-clinical evaluations h) Drug interactions Note: The term Pharmacology used here refers to the classification, mechanism of action, pharmacokinetics, pha...

Detailed Title of the topic 1. General Pharmacology a) Introduction, definitions and scope of pharmacology b) Routes of administration of drugs c) Pharmacokinetics (absorption, distribution, metabolism and excretion) d) Pharmacodynamics e) Factors modifying drug effects f) Drug toxicity - Acute, sub- acute and chronic toxicity. g) Pre-clinical evaluations h) Drug interactions Note: The term Pharmacology used here refers to the classification, mechanism of action, pharmacokinetics, pha...