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Understanding Opioid Tolerance and Its Effects Questions and Answers/verified/latest update Graded A+
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---1January 20252024/2025A+
- Cross-tolerance - Phenomenon where tolerance to one opioid agent results 
in tolerance to others, but not to general CNS depressants. 
Physical Dependence - State where abrupt cessation of drug leads to 
withdrawal symptoms due to adaptive cellular changes. 
Abstinence Syndrome - Symptoms following opioid withdrawal, intensity 
and duration depend on drug half-life and physical dependence. 
Half-life - Time taken for the concentration of a drug in the body to reduce 
by half. 
Morphine - An opio...
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