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Understanding Opioid Tolerance and Its Effects Questions and Answers/verified/latest update Graded A+
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Cross-tolerance - Phenomenon where tolerance to one opioid agent results in tolerance to others, but not to general CNS depressants. Physical Dependence - State where abrupt cessation of drug leads to withdrawal symptoms due to adaptive cellular changes. Abstinence Syndrome - Symptoms following opioid withdrawal, intensity and duration depend on drug half-life and physical dependence. Half-life - Time taken for the concentration of a drug in the body to reduce by half. Morphine - An opio...
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