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Exam (elaborations)
THE PUBLIC HEALTH IMPACT OF PRION DISEASES1
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---25July 20242023/2024A+
- INTRODUCTION 
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), 
are a group of animal and human brain diseases that are uniformly fatal and often 
characterized by a long incubation period and a multifocal neuropathologic picture 
of neuronal loss, spongiform changes, and astrogliosis (3). Investigators believe 
the etiologic agents of TSEs are abnormal conformers of a host-encoded cellular 
protein known as the prion protein. Prion diseases do not characteri...
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