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Screening for cervical cancer with the human papillomavirus test in an area of central Italy with no previous active cytological screening programme
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    Screening for cervical cancer with the human papillomavirus test in an area of central Italy with no previous active cytological screening programme

  • I nfection by high-risk human papillomavirus (HPV) has been recognized as a necessary cause of cervical cancer.1 Evidence from randomized controlled trials showed that HPV testing is more sensitive than cytology in identifying high-grade precancerous lesions, even though it is less specific.2–4 At present, triage of borderline4,5 or low-grade cytology6 with HPV testing is universally accepted and only costeffectiveness limitations represent a matter of concern.6,7 There is also agre...
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