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Exam (elaborations)
Screening for cervical cancer with the human papillomavirus test in an area of central Italy with no previous active cytological screening programme
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---8July 20242023/2024A+
- I 
nfection by high-risk human papillomavirus (HPV) 
has been recognized as a necessary cause of cervical 
cancer.1 
Evidence from randomized controlled trials showed that 
HPV testing is more sensitive than cytology in identifying 
high-grade precancerous lesions, even though it is less 
specific.2–4 
At present, triage of borderline4,5 or low-grade cytology6 
with HPV testing is universally accepted and only costeffectiveness limitations represent a matter of concern.6,7 
There is also agre...
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