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Pharmacology for Nurses. A Pathophysiologic Approach Adams - Holland - Urban (Unit 1)
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---12February 20242023/2024A+
- "Natural" Does Not Always Mean Safer - ◦ Some active chemicals are the same as in 
prescription and OTC medications 
◦ Substituting alternative therapy for established 
medical treatment may prolong condition 
** Oral Drugs Enter Hepatic Portal Circulation (First-Pass Effect) - 1. Drug is absorbed 
2. Drug enters hepatic circulation, goes to liver 
3. Drug is metabolized to inactive form 
4. Drug conjugates and leaves liver 
5. Drug is distributed to general circulation 
6. Many drugs ar...
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