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PATH Block 2: High-Yield Study Guide – Inflammation, Neoplasia, Systemic Pathologies
NewPATH Block 2: High-Yield Study Guide – Inflammation, Neoplasia, 
Systemic Pathologies 
Question 1: What is the fundamental difference between metaplasia and dysplasia? 
ANSWER: Metaplasia is the reversible replacement of one differentiated cell type 
with another. Dysplasia is an abnormal, potentially reversible proliferation of cells with 
cytological and architectural atypia, which is a pre-neoplastic change. 
Question 2: A patient with chronic gastroesophageal reflux disease (GERD) develop...