- Study guides, Class notes & Summaries

Alkylating agents - Answer Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) - Answer Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) - Answer Alkylating agent IV CLL or Indolent NHL Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, hepatotoxicity, ve...

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3 pages

Written in 2023/2024

Grade A+

TestSolver9

Hematologic cancer (blood cancer) - Answer -cancer that begins in bone marrow or immune system cells. -Ex: leukemia, lymphoma, multiple myeloma Leukemia - Answer cancer starts in blood-forming tissues like bone marrow -causes lots of abnormal blood cells to be produced and enter bloodstream Lymphoma - Answer -cancer that begins in immune system (WBC=lymphocytes) -hodgkin and non-hodgkins -B lymphocytes (B cells) - make antibodies (bacteria and viruses, most common lymphoma -T ly...

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13 pages

Written in 2023/2024

Grade A+

TestSolver9

A patient with cancer is considering entering a clinical trial that compares the current standard treatment with an investigational chemotherapeutic agent. This is an example of which phase of a clinical trial? 3 4 1 2 - Answer 3 Answer: Phase 3 clinical trials have a primary goal of establishing efficacy and comparing with the current standard. Reference: Eggert, J. (Ed.). (2017). Cancer basics (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 285(t). What is the sh...

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14 pages

Written in 2023/2024

Grade A+

TestSolver9

infiltration - Answer passage or escape of IV administered drugs into the tissue extravasation - Answer leakage of drugs capable of causing tissue damage into the subcutaneous or subdermal tissue or other unintended sites. irritation - Answer a localized inflammatory reaction at the infusion or injection site flare reaction - Answer a local allergic reaction along a vein caused by irritating drugs. infusion reactions - Answer reactions mediated by the immune system (hyperse...

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26 pages

Written in 2023/2024

Grade A+

TestSolver9

How targeted therapy and chemo differ - Answer -targeted therapies act on specific molecular targets on or within the cells that are associated with cancer, whereas standard chemo act on all rapidly dividing cells-chemo has more SEs-targeted therapy ae chosen and designed to interact with their target on or within the cells, whereas chemo were IDed becaused they kill cells-targeted therapies are often cytostatic (they block tumor cell proliferation) whereas chemo agents are cytotoxic (kill tum...

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7 pages

Written in 2023/2024

Grade A+

TestSolver9

What do alkylating chemotherapy drugs do? - Answer Chemotherapy drugs that are cell cycle nonspecific, so they exert their effects in all phases of the cell cycle. They directly damage DNA to prevent cancer cells from reproducing. They cause breaks in the DNA or cross-linking in a process called alkylation, which causes the drug to interfere with DNA replication. neoadjuvant therapy - Answer a cancer treatment that precedes other primary treatment, such as administering chemotherapy or ra...

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8 pages

Written in 2023/2024

Grade A+

TestSolver9

3 major phases of cell division: - Answer Interphase Mitotic phase Cytokinesis 3 steps of interphase: - Answer First growth phase (G1) Synthesis phase (S phase) Second growth phase (G2) 4 phases of mitosis: - Answer Prophase Metaphase Anaphase Telophase Innate immunity: - Answer Non-specific response, either: 1. Barrier (skin, mucous membranes, flora of skin/gut) 2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages) Adaptive immunity: -...

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20 pages

Written in 2023/2024

Grade A+

TestSolver9

Define neoadjuvant therapy - Answer Treatment is given prior to surgery to shrink the tumor Define adjuvant therapy - Answer Additional cancer treatment given after the primary treatment to lower the risk that the cancer reoccur 3 subcategories of alkylating agents: - Answer 1. Nitrogen mustards 2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as they work similarly) 3. Nitrosoureas Common alkylating agents: - Answer Cyclophosphamide (...

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17 pages

Written in 2023/2024

Grade A+

TestSolver9

Cancer Epidemiology - Answer Study of the distribution and determinants of cancer in population groups Global Cancer Statistics - Answer cancer is the leading cause of disease worldwide Cancer rate - Answer suppouse to increase by 75% to 22 M new cases in 2030 Causes of cancer rate increase - Answer because of increasing tobacco use aging population reproductive dietary and hormonal risk factors Top 5 most commonly diagnosed cancers - Answer Lung (13%) breast (11%)...

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27 pages

Written in 2023/2024

Grade A+

TestSolver9

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy - Answer Main benefit of neoadjuvant chemotherapy (breast cancer patient) A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidit...

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14 pages

Written in 2023/2024

Grade A+

TestSolver9

Key Points for Combination Therapy - Answer Oncology Nurses must consider Consider the potential toxicity related to each drug. Understand the monitoring guidelines for each drug. Have knowledge of clinically significant signs and symptoms ONS Evidence-Based Practice Resources - Answer Evidence-based practice can have positive effects, such as: Improved patient outcomes Increased nurse satisfaction Potential cost savings Risk Factors For Colon Cancer - Answer Increased age is...

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5 pages

Written in 2023/2024

Grade A+

TestSolver9

Goal of radiation - Answer - to irradiate a predefined target volume while minimizing exposure to adjacent normal tissues. - Radiation oncologists and medical oncologists collaborate to determine overall goals and treatment approaches. - Multiple diagnostic procedures are employed to define the tumor volume and prescribe the correct dose of radiation. - Radiation physicists, dosimetrists, oncologists, and therapists use sophisticated hardware and software to model geometric and dosime...

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10 pages

Written in 2023/2024

Grade A+

TestSolver9

Goal of radiation - Answer - to irradiate a predefined target volume while minimizing exposure to adjacent normal tissues. - Radiation oncologists and medical oncologists collaborate to determine overall goals and treatment approaches. - Multiple diagnostic procedures are employed to define the tumor volume and prescribe the correct dose of radiation. - Radiation physicists, dosimetrists, oncologists, and therapists use sophisticated hardware and software to model geometric and dosime...

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10 pages

Written in 2023/2024

Grade A+

TestSolver9

Lesson 1: Foundations to Set the Stage - Answer Focusing on Cellular Structure and Function - Answer The Normal Cell Cycle - Answer -The cell cycle refers to the ordered seres of processes of DNA replication and mitosis, or cell division -Cell nucleus regulates these processes by gathering and processing complexes molecular information Interphase and Mitotic Phase - Answer Cell division produces two identical cells through these two major phases During interphase: - Answ...

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28 pages

Written in 2023/2024

Grade A+

TestSolver9

Verification of Treatment as Planned - Answer -vascular access device appropriate for treatment plan -will patient adhere to plan -is the treatment plan appropriate for patient -do additional referals need to be made for treatment -is there evidenced based rationale for treatment -is the drug a vesicant and are there safety precautions in place -is the drug a cumulative lifetime dose limit and is there tracking in place Patient education - Answer -assess pt's readiness to learn, h...

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3 pages

Written in 2023/2024

Grade A+

TestSolver9

G1 - Answer first growth phase (or first gap) 2 - Answer How many cells are produced each time a cell divides? mitosis - Answer the process of cell division interphase - Answer The time when a cells grows and replicates DNA in preparation for cell division. G1 - Answer most important checkpoint in cell division cell division - Answer Phases of ___________ ___________ include synthesis phase, G1, G2, M phase Chemotherapy and immunotherapy - Answer These treatments ...

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2 pages

Written in 2023/2024

Grade A+

TestSolver9

Lesson 1: Foundations to Set the Stage - Answer Focusing on Cellular Structure and Function - Answer The Normal Cell Cycle - Answer -The cell cycle refers to the ordered seres of processes of DNA replication and mitosis, or cell division -Cell nucleus regulates these processes by gathering and processing complexes molecular information Interphase and Mitotic Phase - Answer Cell division produces two identical cells through these two major phases During interphase: - Answ...

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28 pages

Written in 2023/2024

Grade A+

TestSolver9

Totect - Answer Anecdote for Doxorubicin Warm Compress - Answer Plant alkaloids and etoposide Bleomycin - Answer bad for the lungs Leucovorin - Answer potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components - Answer Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors - Answer used for postmenopausal women- osteoporosis Vesicant Administration - Answer Prior to non-vesicant drugs Through a central l...

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5 pages

Written in 2023/2024

Grade A+

TestSolver9

2024 ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM WITH 100% CORRECT ANSWERS

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19 pages

Written in 2023/2024

Grade A+

BestNursingTestBanks

2024 ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE EXAM WITH 100% CORRECT ANSWERS

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19 pages

Written in 2023/2024

Grade A+

TopNursingTestBanks