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1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to check maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme >>> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 hrs later Cp (pla...

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68 pages

Written in 2021/2022

Grade A+

PossibleA

The modern era of antimicrobial chemotherapy originated with the discovery of 1. penicillin 2. arsenical compounds 3. quinine 4. sulfonamides 5. calomel Answer b: arsenical compounds 1. Morphine was isolated from opium by 1. Paul Ehrlich 2. Gerhard Domagk 3. Friedrich Sertürner 4. Rudolf Buchheim 5. Henry Dale Answer c: Friedrich Sertürner 1. The use of genetic information to guide the choice of drug therapy is called 1. pharmacoepidemiology 2. pharmacogenetics 3. biotechnol...

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97 pages

Written in 2021/2022

Grade A

PossibleA

Nurs 531 Exam 1 2026/2027 | Complete Nursing Study Guide, Practice Questions & Answers

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12 pages

Written in 2026/2027

Grade A+

StuviaExamHub

Nurs 531 Exam Study Notes...

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4 pages

Written in 2024/2025

luzlinkuz

1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to check maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme >>> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 hrs later Cp (plasma...

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75 pages

Written in 2021/2022

Grade A+

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