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Nifurtimox-Eflornithine Combination Therapy for SecondStage Trypanosoma brucei gambiense Sleeping Sickness: A Randomized Clinical Trial in Congo
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9

July 2024

2023/2024

A+
Human African trypanosomiasis (HAT), or sleeping sickness, remains a public health challenge in sub-Saharan Africa, with an estimated 50,000–70,000 new cases per year, of which ∼20,000 are detected and reported [1]. The disease is caused by the protozoan parasite Trypanosoma brucei gambiense, which is transmitted by the tsetse fly (Glossina species), and it progresses from the hemolymphatic first stage to the meningoencephalitic second stage. It is invariably fatal without appropriat...
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