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MedLect USMLE Answers & Rationales | Comprehensive Q& A | Grade A | 100% Correct -The Ultimate Guide for Yr. (2026/2027) Generated: 10/9/2025
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MedLect USMLE Answers & Rationales | Comprehensive Q& A | Grade A | 100% Correct -The Ultimate Guide for Yr. (2026/2027) 
Generated: 10/9/2025 
Question 1: 
A newborn present with severe hypoglycemia, massive hepatomegaly, and failure to thrive. Lab results show hyperuricemia and hyperlipidemia. Which enzyme deficiency is most likely? 
A) Glucose-6-phosphatase 
B)	Alpha-1,4-glucosidase 
C)	Amylo-1,6-glucosidase 
D)	Branching enzyme 
E)	Phosphorylase 
Rationale: 
The clinical picture points towar...
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