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Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin 2 health and lifespan
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39

July 2024

2023/2024

A+
Abstract 21 22 The actin cytoskeleton is a three-dimensional scaffold of proteins that is a regulatory, energy23 consuming network with dynamic properties to shape the structure and function of the cell. Proper 24 actin function is required for many cellular pathways, including cell division, autophagy, chaperone 25 function, endocytosis, and exocytosis. Deterioration of these processes manifests during aging 26 and exposure to stress, which is in part due to the breakdown of the actin...
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