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Lapatinib plus Capecitabine for Brain Metastases in  Patients with Human Epidermal Growth Factor Receptor  2-Positive Advanced Breast Cancer: A Review of the  Anatolian Society of Medical Oncology (ASMO) Experience
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    Lapatinib plus Capecitabine for Brain Metastases in Patients with Human Epidermal Growth Factor Receptor 2-Positive Advanced Breast Cancer: A Review of the Anatolian Society of Medical Oncology (ASMO) Experience

  • Approximately 20–25% of all breast cancers are human epidermal growth factor receptor 2-positive (HER2+) and have historically been associated with poorer disease-free survival (DFS) and overall survival (OS) [1]. For patients with HER2+ metastatic breast cancer (MBC), the use of humanized monoclonal antibody trastuzumab (Herceptin® , Genentech, San Francisco, CA, USA) in combination with chemotherapy has become the standard of care. Approximately one third of patients with MBC ...
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