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PCB 4233; INNATE IMMUNITY AND EARLY HOST DEFENSE STUDY TEST EXAM QUESTIONS AND CORRECT ANSWERS 2026
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---54March 20262025/2026A+
- 8. Yersinia pestis, the causative agent of the bubonic plague, has multiple mechanisms of immune evasion. This Gram-negative bacterium is transmitted from fleas (body temperature 26 deg C) to humans (body temperature 37 deg C) by flea bites. Studies have shown that the lipopolysaccharide (LPS) produced by Y. pestis grown at 37 deg C is about 10-fold less potent at stimulating TLR4 signaling than is the Y. pestis LPS from bacteria grown at 26 deg C. When these two forms of Y. pestis LPS are compa...
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