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Identification of sVSG117 as an Immunodiagnostic Antigen and Evaluation of a Dual-Antigen Lateral Flow Test for the Diagnosis of Human African Trypanosomiasis
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7

July 2024

2023/2024

A+
Introduction Human African Trypanosomiasis (HAT), or African Sleeping Sickness, is caused by two sub-species of Trypanosoma brucei. T. b. gambiense accounts for approximately 95% of HAT infections and occurs across East and Central sub-Saharan Africa. The remaining infections are caused by T. b. rhodesiense in West and Southern Africa. The disease has two stages: Stage 1, where the parasites are limited to the bloodstream, interstitial fluids and lymph of the patient, and stage 2, where ...
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