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Exam (elaborations)
HSCT Exam with 100% correct answers
HSCT 
 
 
HSCT Definition - ANSWER-Process by which abnormal hematopoiesis and/or lymphopoiesis is established by the infusion of ex-vivo PLURIPOTENT stem cells-->HEMATOPOIETIC progenitor cells 
 
Chemotherapy and HSCT - ANSWER--Cancer chemotherapy agents and radiotherapy are destructive to the normal bone marrow cells 
*ex. CARMUSTINE will wipe out BM 
-Therefore, bone marrow suspension is a major limiting factor in the administration of adequate chemotherapy for CURATIVE intent 
 
What doe...
Exam (elaborations)
HSCT Questions with complete solution 2025
PopularHSCT Questions with complete solution 2025 
 
HSCT is the IV infusion of hematopoietic stems cells (HSCs) into a recipient after admin of___ - correct answers HD chemotherapy 
 
Rationales for HSCT 
1. Able to admin_____ as myelosupp. (MLS) is the dose limiting tox (DLT) for many chemo agents 
2. Provide ___marrow 
3. ____effect which essentially will provide an army of T cells to detect and kill tumor cells--> changing tumor microenvironment - correct answers 1. higher doses of chemo which m...
Exam (elaborations)
HSCT Exam Questions & Answers 2023/2024
HSCT Exam Questions & Answers 2023/2024 
 
 
HSCT - ANSWER-The intravenous infusion of hematopoietic progenitor cells to re-establish the function in a patient with damaged or defective bone marrow. 
 
Autologous HSCT - ANSWER-Patients receives their own stem cells 
 
Allogeneic HSCT - ANSWER-Stem cells from various donors 
Syngeneic-identical twin 
Matched sibling donor 
Mis-matched sibling or related donor 
Matched unrelated door (MUD) 
 
BMT - ANSWER-Collection: One (completed in 1-2h) 
G...
Exam (elaborations)
HSCT Exam Questions & Answers 2023/2024
HSCT Exam Questions & Answers 2023/2024 
 
 
Hematopoietic stem cell transplant (HSCT) is also known as _____ - ANSWER-Bone marrow transplant (BMT) or blood and marrow transplant 
 
HSCT is ____ to establish normal hematopoiesis generally after receipt of high-dose chemo +/- radiation - ANSWER-IV infusion of stem cells 
 
Premedication is used to prevent _____ - ANSWER-Infusion reactions 
 
Hydration is used to prevent _____ - ANSWER-Hypotension 
 
Stem cells are ____-preserved - ANSWER-Cryo 
 
...
Exam (elaborations)
HSCT Exam Questions & Answers 2023/2024
HSCT Exam Questions & Answers 2023/2024 
 
 
HSCT Definition - ANSWER-Process by which abnormal hematopoiesis and/or lymphopoiesis is established by the infusion of ex-vivo PLURIPOTENT stem cells-->HEMATOPOIETIC progenitor cells 
 
Chemotherapy and HSCT - ANSWER--Cancer chemotherapy agents and radiotherapy are destructive to the normal bone marrow cells 
*ex. CARMUSTINE will wipe out BM 
-Therefore, bone marrow suspension is a major limiting factor in the administration of adequate chemother...
Exam (elaborations)
470 exam 3 hematopoietic stem cell transplant (HSCT)
470 exam 3 hematopoietic stem cell transplant (HSCT) 
 
 
hematopoiesis - ANSWER-The formation and development blood cells 
 
prenatal hematopoiesis - ANSWER-occurs in the yolk sack, then in the liver, and lastly in the bone marrow 
 
adult hematopoiesis - ANSWER-occurs in the bone marrow and lymphatic tissues. 
 
stem cells - ANSWER-all types of blood cells are derived from them. they have the potential to develop into all types of blood cells, RBC, WBC, Platelets 
 
types of bone marrow - ANSW...