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High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy–Experienced Human Immunodeficiency Virus–Infected Patients in Northern Uganda in the Era of “Test and Treat”: Implications for Cryptococcal Screening Programs
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8

July 2024

2023/2024

A+
Mortality from meningitis in sub-Saharan Africa (SSA) remains high at 19%–68%, and the yeast Cryptococcus neoformans is the most common cause of death among people living with human immunodeficiency virus (HIV) [1, 2]. Annual global deaths from cryptococcal meningitis (CM) are estimated at 181 100, with 135 900 deaths in SSA, and CM is responsible for 15% of all AIDS-related deaths [2]. CM comprises 60% of all meningitis cases in Uganda and is associated with high morbidity and...
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