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First Aid USMLE Step 1: Hematology & Oncology 412 Questions Exam With Complete Solutions | Graded A +
- Exam (elaborations) • 137 pages • 2025
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Clinical use of ironotecan and topotecan? - Correct Answer 
 1. Colon cancer (irinotecan); 
2. Ovarian 
3. Small cell lung cancers (topotecan). 
Clinical use of hydroxurea? - Correct Answer 1. 
Melanoma 
2. CML 
3. Sickle cell disease ( HbF). 
Clinical use of Prednisone, prednisolone - Correct Answer 
 Most commonly used glucocorticoids in cancer 
chemotherapy. Used in:1. CLL 
2. non-Hodgkin lymphoma 
3. immunosuppressants (e.g., in autoimmune diseases)
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