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Exam (elaborations)
ERHS 601 Exam 1 Questions with 100% Correct Answers 2024/2025
ERHS 601 Exam 1 Questions with 100% Correct Answers 2024/2025 
 
 
Where in the body does the toxicant have e the most effect - ANSWERSLungs, heart, kidneys, brain, liver, peripheral nerves 
 
Biotransformation - ANSWERSEnzymatic alteration of xenobiotics can occur as the results of 
• Hydrolysis 
• Oxidation 
• Reduction 
• Conjugation 
Some of these reactions may also occur non-enzymatically 
 
Biotransformation Can Change or Introduce A Functional Group - ANSWERSPhase I reactions...
Exam (elaborations)
ERHS 601 Exam 1 Questions & Answers 2024/2025
PopularERHS 601 Exam 1 Questions & Answers 2024/2025 
 
 
Metabolism involves breaking bonds - ANSWERSStructure (size, shape, electronegativity, electron density) determine where bonds break 
 
Chemical properties that determine function - ANSWERS-Physical state 
-Solubility 
-Reactivity 
-Interaction with biological molecules 
-Atomic size 
-Affinity for electrons 
 
ADME - ANSWERSAbsorption - Uptake 
Distribution - Chemical Fate 
Metabolism - Biotransformation 
Excretion 
 
-Chemical properties deter...