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Early coagulation disorder after allogeneic stem cell transplantation is a strong prognostic factor for transplantation-related mortality, and intervention with recombinant human thrombomodulin improves the outcome: a single-center experience
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10

July 2024

2023/2024

A+
Thrombotic microangiopathy (TMA) and veno-occlusive disease (VOD) are well-known transplantation-related complications induced by coagulation disorder [1–4]. The mortality rates are more than 60–70 % in patients with a severe condition [5]. Basically, patients with SCT are inevitably exposed to mucosal and endothelial damages by conditioning regimens such as irradiation and anticancer drugs, leukocytopenia complicated with infections, hypercytokinemia in an allogeneic immune reaction...
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