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DNA Replication. Exam Mastery Made Easy: Comprehensive Study Guides
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7
May 2024
2023/2024
A
A summary of DNA replication
1. Helicases unwind the parental double helix
2. Single-strand binding proteins stabilize the unwound parental DNA
3. The leading strand is synthesized continuously in the 5' --> 3' direction by DNA
polymerase.
4. The lagging strand is synthesized discontinuously. Primase synthesizes a short RNA
primer, which is extended by DNA polymerase to form an Okazaki fragment.
5. After the RNA primer is replaced by DNA (by another DNA polymerase), DNA ligase
joins...
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