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Clinical Pearls for PNS drugs 1 Study guide
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---16January 20242023/2024A+
- Clinical Pearls for PNS drugs 1 Study guide 
Parasympathetic drugs (cholingeric response) 
 
•	Think SLUDGE 
o	Salivation 
o	Lacrimation 
o	Urination 
o	Defecation 
o	Gastric upset 
o	Emesis 
 
 
Clinical pearls for PNS drugs 2 
Muscarinic agonist vs muscarinic antagonist symptoms 
 
•		If you remember the above acronym then its important to remember if the drug is an agonist of muscarine receptors or an antagonist and then just associate 
symptoms of sludge with agonist and the OPPOSITE ef...
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