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Exam (elaborations)
CCNM BAS209 Pharmacology Pre-Midterm Qs exam graded A+ 2024/2025
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---12January 20252024/2025A+
- What is the pKa of a drug? - ️️The pH at which the drug is 50% ionized and 50% noniodized (aka equal deprotonated and protonated forms of the drug) 
For drugs to be absorbed, do we want them charged or uncharged? - ️️Uncharged 
What is the pH of the stomach vs. the small intestine? - ️️Stomach: pH around 1 
Small intestine: neutral pH around 7 
You develop a drug and decide to name it BLACKPINK. BLACKPINK has a pKa of 3. 
Would it be better absorbed in the stomach or small intestine?...
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