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A Hierarchical Learning Approach to Calibrate Allele Frequencies for SNP Based Genotyping of DNA Pools
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7

August 2024

2024/2025

A+
Singular Nucleotide Polymorphisms (SNPs) based genotyping is a fast and cost effective approach to identify functionally important polymorphisms of a species [1]. Such gene markers can be linked with disease, complex traits or be used to provide family information. Multiplex microarray systems have been developed for SNP genotyping to provide sufficiently dense coverage for genome wide association studies [2, 3]. For instance, Affymetrix array technology [2] can interrogate 906,6...
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