Advanced Pharmacology

NR 566 Week 1 Notes Ch. 21, 33, & 41 Chapter 21: Drugs Affecting the Endocrine System Pharmacokinetics  Absorption and Distribution o All oral bisphosphonates potentially cause esophagitis and gastric irritation o Absorption and bioavailability of oral doses are significantly reduced by the presence of food in the gut or other preparations containing divalent cations. o To enhance absorption, the patient takes the drug with 8 oz of water, No other food or drink should be ingested, and...