FSN 420
University Of Maine
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Exam (elaborations)
REVIEW FOR EXAM #3 FSN 420
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---22June 20222021/2022A+
- REVIEW FOR EXAM #3 
1. Pathogenesis of atherosclerosisknow the specific steps and the changes that take place in 
the endothelium 
Pathogenesis: 
- Atherogenic stimuli (inflammation) or mechanical injury: cells express adhesion molecules and growth factors 
that lead to recruitment of leukocytes in inflammatory response to injury 
- Leukocytes adhere and migrate into vessel wall, localize subendothelially and develop foam cells 
- Foam cells release growth factors and cytokines that prom...
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