NURS 615 (NURS615)

NURS 615 WEEK 8: ADVANCED PHARMACOTHERAPEUTICS STUDY GUIDE QUESTIONS & COMPLETE DETAILED ANSWERS (LATEST 2025/2026 UPDATE) 1. Difference between low-dose and high-dose colchicine? a. Colchicine is used for Gout. Low-dose colchicine is given for the initial flare up at 1.2 mg, followed by 0.6 mg and hour later. High dose colchicine is 1.2 mg followed by 0.6 mg every 4-6 hours for a total of 4.8 mg until relief is achieved. Low dose colchicine is as effective as high dose colchicine with fe...

• Pain Management – • o Know the treatment of acute pain – what medications are firstline? o For non-cancer pain, mild-to-mod pain (aches, muscle pain, mild injuries): NSAIDs, anticonvulsants, tylenol, muscle relaxants What would you prescribe first when treating acute mild musculoskeletal pain? Think of the guidelines and the Shadow Health assignment: ibuprofen • NSAIDS – pain relief, antipyretic, anti-inflammatory effects o Adverse effects – GI: nausea, heartburn, minor HA...

Respiratory Medications Study Guide 1. Bronchodilators A. Beta-2 Agonists • MOA: o Bind to beta-2 receptors on airway smooth muscle → activate cyclic AMP pathway → muscle relaxation → bronchodilation o Inhibit release of hypersensitivity mediators (mast cells) o Some beta-1 receptor activity → possible cardiac side effects Pharmacokinetics: o Absorbed in bronchi → metabolized in liver → excreted in urine Adverse Effects: o Tachycardia, tremors Precautions: o Monitor in ...

What are characteristics of serotonin syndrome? (Ansnausea, diarrhea, sweating, hyperthermia, myoclonic jerking, tremor, agitation, disorientation, HTN, delirium, death What medication is approved for depression with low energy? (Ansvenlafaxine (Effexor) (SNRI) How does Lithium act as a mood stabilizer? (AnsIt replaces sodium during depolarization so it stops the transmission of electrical impulses What is important patient teaching for Lithium? (AnsEat a diet with consistent levels of ...

What are examples of 1st generation antihistamines? (Ans- 1. chlorpheniramine 2. diphenhydramine (Benadryl) 3. hydroxyzine (Atarax) 4. promethazine (Phenergan) 1st generation antihistamines have a GREAT effect on what? (Ans- central nervous system What should antihistamines not be used with? (Ans- ETOH What are adverse effects of 1st generation antihistamines? (AnsHIGH anticholinergic effects: 1. sedation 2. tinnitus 3. coordination problems4. fatigue, HA, irritability, nervousness...

What is Exenatide used for and what is an advantage of it? (AnsThis class of drugs is used for treatment of type 2 diabetes. One of their advantages over older insulin secretagogues such as sulfonylureas or meglitinides is that they have a lower risk of causing hypoglycemia. Exenatide and how it works (AnsExenatide is a synthetic version of exendin-4 hormone found in the saliva of the Gila monster. It displays biological properties similar to human glucagon-like peptide or GLP-1, a regula...

What are the main side effects of MAOIs (Ans- dizziness, H/A, insomnia, restlessness, hypotension What can happen if foods containing tyramine (aged cheese/meats, alcohol) are consumed while on MAOI (Ans- hypertensive crisis Before starting a different med how long should it be after weaning off MAOI? (Ans- at least 2 weeks What are the main side effects of SNRIs & NRIs (Ansheadache, somnolence, nausea, (dry mouth, constipation=anticholinergic effects), sexual side effects, palpitation...

What is the efficacy of a drug? (Ans- Efficacy is the maximum response achievable from a drug. Effectiveness refers to the ability of the drug to produce a beneficial effect. On the drug concentration curve what is the first sign of a therapeutic effect? (Ans- The onset of action What is the purpose of a peak and trough level? (Ans- To determine if the drug is in therapeutic range. Describe the purpose of blood brain barrier (AnsThe BBB is a highly selective permeability barrier that s...

Shadow Health Focused Exam Hypertension And Type 2 Diabetes Week 10 Subjective Data Collection 20of 20 (100.0%) Updated Solutions