Comprehensive Basic Science
Kaplan University
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Exam (elaborations)
Comprehensive Basic Science Exam (CBSE) Review Set I (with COMPLETE SOLUTION) Study Guide
Chagas Disease - Caused by Trypanosoma cruzi parasite passed in the feces of 
Reduviidae/kissing bug 
Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing 
inflammatory infiltrates into myocytes; stains with Giemsa & Wright 
Romana sign occurs when portal of entry is the conjunctiva or eyelid 
May resulting in: 
Enlarged heart- CHF, sudden cardiac arrest 
Enlarged esophagus- difficulty swallowing 
Enlarged colon- abdominal pain or constipation 
Treat with benznidazole...
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