NUR 2214
Florida State University
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Exam (elaborations)
NUR 2214 Study Guide Summer 2020 Exam 3
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---43July 20232022/2023A+
- NUR 2214 Study Guide Summer 2020 Exam 3Sickle Cell Anemia 
•	Definition/Pathophysiology 
o	The clinical features of SCA are primarily the result of 
	(1) obstruction caused by the sickled RBCs with other cells 
	(2) vascular inflammation 
	(3) Increased RBC destruction,****** abnormal adhesion, entanglement, and enmeshing of rigid sickle-shaped cells accompanied by the inflammatory process intermittently blocks the microcirculation causing vaso-occlusion. 
•	The resultant absence ...
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Exam (elaborations)
NUR 2214 Study Guide Spring 2020 Exam 3
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---23July 20232022/2023A+
- NUR 2214 Study Guide Spring 2020 Exam 31.	Sickle cell anemia 
a.	Definition/Pathophysiology 
•	Sickle cell disease (SCD), which used to be called sickle cell anemia, is a genetic disorder that results in chronic anemia, pain, disability, organ damage, increased risk for infection, and early death 
•	This disorder results in the formation of abnormal hemoglobin chains. 
•	the clumped masses of sickled RBCs block blood flow, known as a vaso-occlusive event (VOE). VOE leads to further tissue ...
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