NURS 323 (NURS323)
California State University - Fullerton
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Exam (elaborations)
NURS 323 Pharm - Final Exam
Nitroglycerin MOA - converts nitric oxide to active form, which causes 
DILATION of arterial and venous vessels, decreasing myocardial oxygen demand 
Venous dilation causes... - decreased preload and peripheral vascular resistance 
Arterial dilation causes... - reduced systemic vascular resistance and pressure, 
which causes decreased afterload 
Nitroglycerin pharmacokinetics - - lipid-soluble --> easily crosses membranes 
- FIRST-PASS EFFECT, so not usually given PO 
**important to educate p...